Effects of a 60 Hz magnetic field on central cholinergic systems of the rat

Journal Article · Mon Mar 15 00:00:00 EST 1993 · Bioelectromagnetics (New York); (United States)

DOI:https://doi.org/10.1002/bem.2250140104· OSTI ID:6440373

Lai, H; Carino, M A; Horita, A; Guy, A W ^[1]

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1. Univ. of Washington, Seattle (United States)

The authors studied the effects of an acute exposure to a 60 Hz magnetic field on sodium-dependent, high-affinity choline uptake in the brain of the rat. Decreases in uptake were observed in the frontal cortex and hippocampus after the animals were exposed to a magnetic field at flux densities [>=] 0.75 mT. These effects of the magnetic field were blocked by pretreating the animals with the narcotic antagonist naltrexone, but not by the peripheral opioid antagonist, naloxone methiodide. These data indicate that the magnetic-field-induced decreases in high-affinity choline uptake in the rat brain were mediated by endogenous opioids in the central nervous systems.

• OSTI ID: 6440373
• Journal Information: Bioelectromagnetics (New York); (United States), Vol. 14:1; ISSN 0197-8462
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BRAIN
SENSITIVITY
CHOLINE
UPTAKE
ELECTROMAGNETIC FIELDS
BIOLOGICAL EFFECTS
ACUTE EXPOSURE
GHZ RANGE 01-100
RATS
ALCOHOLS
AMINES
AMMONIUM COMPOUNDS
ANIMALS
BODY
CENTRAL NERVOUS SYSTEM
DRUGS
FREQUENCY RANGE
GHZ RANGE
HYDROXY COMPOUNDS
LIPOTROPIC FACTORS
MAMMALS
NERVOUS SYSTEM
ORGANIC COMPOUNDS
ORGANS
QUATERNARY COMPOUNDS
RODENTS
VERTEBRATES
560400* - Other Environmental Pollutant Effects