Effect of digoxin on serum and urinary cation changes on acute induction to high altitude

Journal Article · Sun Apr 01 00:00:00 EST 1984 · Aviat., Space Environ. Med.; (United States)

OSTI ID:6403029

Ohri, V C; Chatterji, J C; Sachdev, Y R; Das, B K; Akhtar, M; Tiwari, S C; Bhattacharji, P; Behl, A; Dutta, S K

Forty subjects each were rapidly inducted by road to altitudes of 3200 and 3771 meters (m). Half of subjects at each altitude were maintained on digoxin and the other half received placebos. The digoxin group showed higher serum potassium at both altitudes. Serum sodium remained unaltered. When compared to control groups, urinary volume changes were less marked in the digoxin group. Similarly, the alterations in calcium and magnesium in serum and urine at 3771 m were less pronounced. However, none of these changes in the digoxin groups were statistically significant when compared with control groups. 21 references.

• Research Organization: Armed Forces Medical Services, New Delhi, India
• OSTI ID: 6403029
• Journal Information: Aviat., Space Environ. Med.; (United States), Vol. 55
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BLOOD PLASMA
CATIONS
DIGOXIN
BIOLOGICAL EFFECTS
URINE
DRUGS
POTASSIUM
SODIUM
ALKALI METALS
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BLOOD
BODY FLUIDS
CARBOHYDRATES
CARDIAC GLYCOSIDES
CARDIOTONICS
CARDIOVASCULAR AGENTS
CHARGED PARTICLES
DIGITALIS GLYCOSIDES
ELEMENTS
GLYCOSIDES
IONS
MATERIALS
METALS
ORGANIC COMPOUNDS
WASTES
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)