Temperature rise during photoradiation therapy of malignant tumors

Journal Article · Sat Jan 01 00:00:00 EST 1983 · Med. Phys.; (United States)

DOI:https://doi.org/10.1118/1.595373· OSTI ID:6376155

Svaasand, L O; Doiron, D R; Dougherty, T J

This report discusses the optical and thermal distribution during photoradiation therapy of malignant tumors. Emphasis is put on the therapeutic procedure with the light dose delivered through an inserted optical fiber. Theoretical predictions and experimental results indicate that the temperature rise during the procedure may give rise to hyperthermal cell kill. The report discusses the extent of the regions with hyperthermal bioeffects in terms of tissue parameters as optical absorption and scattering, thermal conductivity, specific heat, blood flow, and optical dose parameters as optical power and exposure time. Key words: photoradiation therapy, hematoporphyrin derivative, hyperthermia

• Research Organization: Division of Physical Electronics, University of Trondheim, N-7034 Trondheim NTH, Norway
• OSTI ID: 6376155
• Journal Information: Med. Phys.; (United States), Vol. 10:1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
NEOPLASMS
RADIOTHERAPY
TEMPERATURE DISTRIBUTION
ABSORPTION
BLOOD FLOW
ELECTROMAGNETIC RADIATION
HYPERTHERMIA
IN VIVO
OPTICAL FIBERS
THERMAL CONDUCTIVITY
TISSUES
BODY
BODY TEMPERATURE
DISEASES
FIBERS
MEDICINE
NUCLEAR MEDICINE
PHYSICAL PROPERTIES
RADIATIONS
RADIOLOGY
THERAPY
THERMODYNAMIC PROPERTIES
550603* - Medicine- External Radiation in Therapy- (1980-)