Isolation and characterization of Klebsiella pneumoniae unencapsulated mutants

Journal Article · Sun Jan 01 00:00:00 EST 1989 · J. Clin. Microbiol.; (United States)

OSTI ID:6323413

Benedi, V J; Ciurana, B; Tomas, J M

Klebsiella pneumoniae mutants were obtained after UV irradiation and negative selection with anticapsular serum. Unencapsulation, rather than expression of a structurally altered capsule, was found in the mutants. The mutant strains showed no alterations in their outer membrane proteins and lipopolysaccharide, and a great similarity with the wild type in the properties tested (serum resistance, antimicrobial sensitivity, and lipopolysaccharide-specific bacteriophage sensitivity), with the exception of a higher cell surface hydrophobicity and resistance to bacteriophage FC3-9.

• Research Organization: Universidad de las Islas Baleares, Palma de Mallorca (Spain)
• OSTI ID: 6323413
• Journal Information: J. Clin. Microbiol.; (United States), Vol. 27:1
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
KLEBSIELLA
GENETIC RADIATION EFFECTS
MUTATIONS
RADIOINDUCTION
RADIATION INDUCED MUTANTS
SENSITIVITY
BACTERIOPHAGES
CELL MEMBRANES
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BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CARBOHYDRATES
CELL CONSTITUENTS
ELECTROMAGNETIC RADIATION
GENETIC EFFECTS
LIPIDS
MEMBRANES
MICROORGANISMS
MUTANTS
ORGANIC COMPOUNDS
PARASITES
POLYSACCHARIDES
PROTEINS
RADIATION EFFECTS
RADIATIONS
SACCHARIDES
VIRUSES
560130* - Radiation Effects on Microorganisms