Stochastic models for cells exposed to ionizing radiation

Technical Report · Wed Jan 01 00:00:00 EST 1986

OSTI ID:6322867

Yang, G L; Swenberg, C E

The stochastic model for survivability of cells subjected to ionizing radiation initially formulated by Neyman and Puri is modified to include both the plating time to cell proliferation and dose saturation of potential lethal damage. This necessitates a reformulation of the cell survival and mutation probability. Based on the new model the authors derive the the probability of occurrence for several experimental end points. The predictions of the model compare favorably to data for diploid yeast cells irradiated with 30-MeV electrons.

• Research Organization: Armed Forces Radiobiology Research Inst., Bethesda, MD (USA)
• OSTI ID: 6322867
• Report Number(s): AD-A-181791/5/XAB; AFRRI-SR-86-52
• Resource Relation: Other Information: Pub. in Modelling of Biomedical Systems, 85-89(1986)
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
PLANT CELLS
BIOLOGICAL RADIATION EFFECTS
YEASTS
DAMAGE
MATHEMATICAL MODELS
MUTATIONS
PLATING
PROBABILITY
STOCHASTIC PROCESSES
BIOLOGICAL EFFECTS
DEPOSITION
FUNGI
MICROORGANISMS
PLANTS
RADIATION EFFECTS
SURFACE COATING
560140* - Radiation Effects on Plants