Effect of x irradiation on the capacity of transfer RNA to act as substrate for guanine-tRNA transferase

Journal Article · Sat Aug 01 00:00:00 EDT 1981 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3575589· OSTI ID:6315000

Walden, T; Farkas, W R

Observation on the guanine-accepting ability of x-irradiated wheat germ tRNA shows 50% inactivation at 57,000 rad with an unusual sawtooth pattern at low doses. The sawtooth has peaks at 1330 and 3300 rad and can be modified by bovine serum albumin. RPC-5 profiles of guanylated irradiated and unirradiated tRNA are identical, indicating that irradiation does not result in abnormal tRNA species, that ordinarily are not substrates for this enzyme, becoming substrates.

• Research Organization: Univ. of Tennessee, Knoxville
• OSTI ID: 6315000
• Journal Information: Radiat. Res.; (United States), Vol. 87:2
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
SUBSTRATES
BIOLOGICAL RADIATION EFFECTS
TRANSFER RNA
GUANINE
NUCLEOTIDYLTRANSFERASES
X RADIATION
AMINES
BIOLOGICAL EFFECTS
ELECTROMAGNETIC RADIATION
ENZYMES
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
IONIZING RADIATIONS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PHOSPHORUS-GROUP TRANSFERASES
PURINES
RADIATION EFFECTS
RADIATIONS
RNA
TRANSFERASES
560110* - Radiation Effects on Biochemicals- (-1987)