Comparison of dobutamine infusion and supine bicycle exercise for radionuclide cardiac stress testing
A comparison is made of the inotropic drug dobutamine to supine bicycle exercise as a means of inducing stress in radionuclide ventriculography studies. Dobutamine has the following properties, making it favorable for widespread usage: 1) ability to be given safely in a peripheral vein, 2) rapid onset, and 3) short duration of action. Each patient underwent supine bicycle progressive resistance testing of 2 minutes per stage followed 30 minutes later by dobutamine administration. Accuracy of diagnosis was 0.93 and sensitivity was 0.89 with dobutamine, while with bicycle the accuracy was 0.93 and sensitivity was 0.94. While not designed to replace supine bicycle testing, incremental infusions of dobutamine appear to be nearly equal in accuracy and sensitivity, providing a satisfactory technique for cardiac evaluation of previously excluded patients.
- Research Organization:
- Edward Hines Jr. United States Veterans Administration Hospital, Hines, IL
- OSTI ID:
- 6306799
- Journal Information:
- Clin. Nucl. Med.; (United States), Vol. 9:5
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
CARDIOTONICS
BIOLOGICAL EFFECTS
CARDIOVASCULAR DISEASES
DIAGNOSIS
EXERCISE
HEART
RADIOISOTOPE SCANNING
ACCURACY
BIOLOGICAL STRESS
COMPARATIVE EVALUATIONS
PATIENTS
SENSITIVITY
STATISTICAL DATA
BODY
CARDIOVASCULAR AGENTS
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DATA
DISEASES
DRUGS
INFORMATION
NUMERICAL DATA
ORGANS
550601* - Medicine- Unsealed Radionuclides in Diagnostics