skip to main content

Title: High-dose fractionated radiation therapy for select patients with brain metastases

Four patients with metastases to the brain were treated by high-dose fractionated radiation therapy. In all four cases, a complete response and prolonged disease-free survival could be documented. Unlike the standard therapy for such patients (i.e., craniotomy and postoperative irradiation), high-dose fractionated radiation therapy carries no operative risk and can encompass multiple brain metastases and metastases in deep or critical intracranial sites. The risk of radiotherapy side effects in the brain is discussed.
Authors:
 [1] ; ; ; ;
  1. (City of Hope National Medical Center, Duarte, CA)
Publication Date:
OSTI Identifier:
6297643
Resource Type:
Journal Article
Resource Relation:
Journal Name: Radiology; (United States); Journal Volume: 140:2
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; BRAIN; DELAYED RADIATION EFFECTS; NECROSIS; RADIOINDUCTION; NERVOUS SYSTEM DISEASES; RADIOTHERAPY; EVALUATION; SIDE EFFECTS; DOSE RATES; FRACTIONATED IRRADIATION; LOCAL IRRADIATION; METASTASES; PATIENTS; RISK ASSESSMENT; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; CENTRAL NERVOUS SYSTEM; DISEASES; IRRADIATION; MEDICINE; NERVOUS SYSTEM; NUCLEAR MEDICINE; ORGANS; PATHOLOGICAL CHANGES; RADIATION EFFECTS; RADIOLOGY; THERAPY 560151* -- Radiation Effects on Animals-- Man; 550603 -- Medicine-- External Radiation in Therapy-- (1980-)