Application of microvascular free osteocutaneous flaps in the management of post-radiation recurrent oral cancer
Fifty-nine patients underwent free flap osteocutaneous reconstruction that consisted of flaps of the dorsum of the foot in 26 patients and iliac crest flaps in 33 with a success rate of 92 percent and a mortality rate of 1.6 percent. These flaps, which require the expertise of microvascular surgeons, are time-consuming and complicate operating room and time management, but they represent a remarkable advance in reconstruction that can facilitate cosmetic and functional recovery of the patient. In particular, they promote healing in radiation-recurrent oral cancer and represent a definitive form of management for established radionecrosis of the mandible. The large volume of tissue available with iliac crest osteocutaneous grafts permits the management of patients with extensive cancer involving the skin, mucosa, and bone, but cancer control may still be disappointing and there is a need for improved adjuvant chemotherapy protocols. This technique appears to be a dependable, repeatable, and significant advance in management of the patient with head and neck cancer.
- Research Organization:
- Univ. of Toronto, Ontario, Canada
- OSTI ID:
- 6288196
- Journal Information:
- Am. J. Surg.; (United States), Vol. 4
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
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OSTEORADIONECROSIS
NEOPLASMS
RADIOINDUCTION
RADIOTHERAPY
SIDE EFFECTS
HEAD
NECK
ORAL CAVITY
PLASTIC SURGERY
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
DIGESTIVE SYSTEM
DISEASES
INJURIES
LOCAL RADIATION EFFECTS
MEDICINE
NECROSIS
NUCLEAR MEDICINE
ORGANS
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIATION INJURIES
RADIOLOGY
SKELETAL DISEASES
SKELETON
SKULL
SURGERY
THERAPY
550603* - Medicine- External Radiation in Therapy- (1980-)
560151 - Radiation Effects on Animals- Man