Protein targeting to the nuclear pore. What can we learn from plants. [Nuclear pore complex]
- Michigan State Univ., East Lansing, MI (United States). DOE Plant Research Lab.
Characteristic of eukaryotic cells are the numerous types of membrane-bound organelles or compartments found in the cytoplasm, with each type carrying out an essential function for the cell. The spatial separation of proteins and biochemical pathways typical of the various types of organelles requires selective targeting apparatuses. Because each type of organelle contains its own targeting apparatus, proteins destined for a particular organelle must contain the proper targeting signal(s) for entry. These signal-dependent targeting pathways ensure that proteins are targeted to the proper organelle. Understanding how proteins are targeted to the different types of organelles is an important goal in the field of cell biology. In plants recent studies have highlighted a number of unusual features, and as the understanding of import in plants increases, the authors have gained new insights, such as a model for the targeting of proteins from the cytoplasm to the NPC. These advances will contribute to further expansion of the knowledge of nuclear import in eukaryotes.
- Sponsoring Organization:
- USDOE; USDOE, Washington, DC (United States)
- DOE Contract Number:
- FG02-91ER20021
- OSTI ID:
- 6281321
- Journal Information:
- Plant Physiology; (Bethesda), Vol. 119:4; ISSN 0032-0889
- Country of Publication:
- United States
- Language:
- English
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