Pilot studies of superfractionated radiotherapy and combination chemotherapy in limited oat cell carcinoma of the bronchus

Journal Article · Mon Oct 01 00:00:00 EDT 1984 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(84)90275-X· OSTI ID:6268459

Hodson, D I; Malaker, K; Meikle, A L; Levitt, M

There are sound radiobiologic and suggestive clinical rationale for superfractionating the radiotherapeutic regimens employed for the therapy of rapidly growing malignancies. Oat cell carcinoma of the bronchus is such a tumor. The authors report their experience combining aggressive systemic combination chemotherapy with supperfractionated radiotherapy for the treatment of limited oat cell carcinoma of the bronchus. Overall, patient tolerance was satisfactory and a complete remission rate of 74% was achieved. It remains to be proven, in a prospective randomized fashion, whether this approach is superior to current conventional management.

• Research Organization: Univ. of Manitoba, Winnipeg, MB (Canada)
• OSTI ID: 6268459
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 10:10
• Country of Publication: United States
• Language: English

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