Vascular changes in popliteal lymph nodes due to antigen challenge in normal and lethally irradiated mice

Journal Article · Mon Jun 01 00:00:00 EDT 1987 · Scan. Microsc.; (United States)

OSTI ID:6243467

Steeber, D A; Erickson, C M; Hodde, K C; Albrecht, R M

The microvascular system of the murine popliteal lymph node was investigated using scanning electron microscopy of microcorrosion casts. Time-dependent changes in the microvasculature following regional antigen challenge in normal and lymphocyte-depleted mice were studied. Normal lymph node microvasculature exhibited a significant increase in both the vascular bed and post-capillary venules containing high-endothelium in response to antigen challenge. Lymph nodes of lymphocyte-depleted mice showed no microvascular size increase following antigen challenge and a reduction in the amount of high-endothelium was observed.

• Research Organization: Univ. of Wisconsin, Madison
• OSTI ID: 6243467
• Journal Information: Scan. Microsc.; (United States), Vol. 1:2
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
LYMPH NODES
MORPHOLOGICAL CHANGES
ANTIGENS
BIOLOGICAL RADIATION EFFECTS
CAPILLARIES
ENDOTHELIUM
LETHAL IRRADIATION
MICE
SCANNING ELECTRON MICROSCOPY
TIME DEPENDENCE
ANIMAL TISSUES
ANIMALS
BIOLOGICAL EFFECTS
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
ELECTRON MICROSCOPY
IRRADIATION
LYMPHATIC SYSTEM
MAMMALS
MICROSCOPY
ORGANS
RADIATION EFFECTS
RODENTS
TISSUES
VERTEBRATES
560152* - Radiation Effects on Animals- Animals