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Title: Pineal and ectopic pineal tumors: the role of radiation therapy. [X ray; /sup 60/Co]

Abstract

Seventeen patients with pineal tumors and one ectopic (suprasellar) germinoma were treated with radiation therapy. Surgery was restricted to decompression in 16 patients, and only two patients had resection of the tumor. Thirteen of 18 patients are alive without evidence for disease with a ten-year surrvival rate of 88%. The tumor dose ranged from 4000 rads to 6000 rads. No age or dose dependence in survival was noted, but patients with whole brain irradiation or generous volume to include ventricular system had better survival. No case of spinal metastasis was noted. The possibility of increased incidence of meningeal seeding following surgical intervention is considered. From their data, the authors feel that radiation therapy with or without surgical decompression should be the primary treatment for pinealoma. Surgery can be used for diagnosis and/or treatment of patients who show delayed response to radiation. Recommendation is made for the use of whole brain irradiation to 4000 rads followed by a boost to the tumor area to 5000 rads.

Authors:
; ; ; ;
Publication Date:
Research Org.:
Univ. of Minnesota, Minneapolis
OSTI Identifier:
6229359
Resource Type:
Conference
Journal Name:
Cancer; (United States)
Additional Journal Information:
Journal Volume: 48:3; Conference: 66. scientific assembly and annual meeting of the Radiological Society of North America, Dallas, Texas, USA, 16 Nov 1980
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; ATROPHY; RADIOINDUCTION; EYES; BIOLOGICAL RADIATION EFFECTS; NERVOUS SYSTEM DISEASES; RADIOTHERAPY; SIDE EFFECTS; COBALT 60; GAMMA RADIATION; LINEAR ACCELERATORS; LOCAL IRRADIATION; METASTASES; PATIENTS; PINEAL GLAND; SURGERY; X RADIATION; ACCELERATORS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BODY; BODY AREAS; COBALT ISOTOPES; DISEASES; ELECTROMAGNETIC RADIATION; FACE; GLANDS; HEAD; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IONIZING RADIATIONS; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; MINUTES LIVING RADIOISOTOPES; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANS; PATHOLOGICAL CHANGES; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RADIOLOGY; SENSE ORGANS; THERAPY; YEARS LIVING RADIOISOTOPES; 560151* - Radiation Effects on Animals- Man; 550603 - Medicine- External Radiation in Therapy- (1980-)

Citation Formats

Rao, Y T.R., Medini, E, Haselow, R E, Jones, Jr, T K, and Levitt, S H. Pineal and ectopic pineal tumors: the role of radiation therapy. [X ray; /sup 60/Co]. United States: N. p., 1981. Web.
Rao, Y T.R., Medini, E, Haselow, R E, Jones, Jr, T K, & Levitt, S H. Pineal and ectopic pineal tumors: the role of radiation therapy. [X ray; /sup 60/Co]. United States.
Rao, Y T.R., Medini, E, Haselow, R E, Jones, Jr, T K, and Levitt, S H. 1981. "Pineal and ectopic pineal tumors: the role of radiation therapy. [X ray; /sup 60/Co]". United States.
@article{osti_6229359,
title = {Pineal and ectopic pineal tumors: the role of radiation therapy. [X ray; /sup 60/Co]},
author = {Rao, Y T.R. and Medini, E and Haselow, R E and Jones, Jr, T K and Levitt, S H},
abstractNote = {Seventeen patients with pineal tumors and one ectopic (suprasellar) germinoma were treated with radiation therapy. Surgery was restricted to decompression in 16 patients, and only two patients had resection of the tumor. Thirteen of 18 patients are alive without evidence for disease with a ten-year surrvival rate of 88%. The tumor dose ranged from 4000 rads to 6000 rads. No age or dose dependence in survival was noted, but patients with whole brain irradiation or generous volume to include ventricular system had better survival. No case of spinal metastasis was noted. The possibility of increased incidence of meningeal seeding following surgical intervention is considered. From their data, the authors feel that radiation therapy with or without surgical decompression should be the primary treatment for pinealoma. Surgery can be used for diagnosis and/or treatment of patients who show delayed response to radiation. Recommendation is made for the use of whole brain irradiation to 4000 rads followed by a boost to the tumor area to 5000 rads.},
doi = {},
url = {https://www.osti.gov/biblio/6229359}, journal = {Cancer; (United States)},
number = ,
volume = 48:3,
place = {United States},
year = {Sat Aug 01 00:00:00 EDT 1981},
month = {Sat Aug 01 00:00:00 EDT 1981}
}

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