Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
Journal Article
·
· J. Virol.; (United States)
OSTI ID:6204324
The authors considered an infectious molecular clone of acquired immunodeficiency syndrome-associated retrovirus. Upon transfection, this clone directed the production of infectious virus particles in a wide variety of cells in addition to human T4 cells. The progeny, infectious virions, were synthesized in mouse, mink, monkey, and several human non-T cell lines, indicating the absence of any intracellular obstacle to viral RNA or protein production or assembly. During the course of these studies, a human colon carcinoma cell line, exquisitely sensitive to DNA transfection, was identified.
- Research Organization:
- National Institutes of Health, Bethesda, MD (USA)
- OSTI ID:
- 6204324
- Journal Information:
- J. Virol.; (United States), Vol. 59:2
- Country of Publication:
- United States
- Language:
- English
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+3 more
Related Subjects
59 BASIC BIOLOGICAL SCIENCES
AIDS
PATHOGENESIS
AIDS VIRUS
BIOSYNTHESIS
DNA
AUTORADIOGRAPHY
CARCINOMAS
DNA REPLICATION
HYBRIDIZATION
LYMPHOCYTES
MAN
PATIENTS
PHOSPHORUS 32
RECEPTORS
TUMOR CELLS
ANIMAL CELLS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CONNECTIVE TISSUE CELLS
DAYS LIVING RADIOISOTOPES
DISEASES
HEMIC DISEASES
IMMUNE SYSTEM DISEASES
INFECTIOUS DISEASES
ISOTOPES
LEUKOCYTES
LIGHT NUCLEI
MAMMALS
MATERIALS
MEMBRANE PROTEINS
MICROORGANISMS
NEOPLASMS
NUCLEI
NUCLEIC ACID REPLICATION
NUCLEIC ACIDS
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
PARASITES
PHOSPHORUS ISOTOPES
PRIMATES
PROTEINS
RADIOISOTOPES
SOMATIC CELLS
SYNTHESIS
VERTEBRATES
VIRAL DISEASES
VIRUSES
550701* - Microbiology- Tracer Techniques
AIDS
PATHOGENESIS
AIDS VIRUS
BIOSYNTHESIS
DNA
AUTORADIOGRAPHY
CARCINOMAS
DNA REPLICATION
HYBRIDIZATION
LYMPHOCYTES
MAN
PATIENTS
PHOSPHORUS 32
RECEPTORS
TUMOR CELLS
ANIMAL CELLS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CONNECTIVE TISSUE CELLS
DAYS LIVING RADIOISOTOPES
DISEASES
HEMIC DISEASES
IMMUNE SYSTEM DISEASES
INFECTIOUS DISEASES
ISOTOPES
LEUKOCYTES
LIGHT NUCLEI
MAMMALS
MATERIALS
MEMBRANE PROTEINS
MICROORGANISMS
NEOPLASMS
NUCLEI
NUCLEIC ACID REPLICATION
NUCLEIC ACIDS
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
PARASITES
PHOSPHORUS ISOTOPES
PRIMATES
PROTEINS
RADIOISOTOPES
SOMATIC CELLS
SYNTHESIS
VERTEBRATES
VIRAL DISEASES
VIRUSES
550701* - Microbiology- Tracer Techniques