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Title: Routine clinical estimation of rectal, rectosigmoidal, and bladder doses from intracavitary brachytherapy in the treatment of carcinoma of the cervix. [X ray; /sup 137/Cs]

An evaluation of rectal, rectosigmoidal, and bladder doses from intracavitary brachytherapy in carcinoma of the cervix has been initiated on a routine basis in an effort to obtain the optimum radiotherapeutic dose. Contrast radiography on a radiotherapy simulator is used to image the rectum and bladder, and dose rates are determined at predesignated reference points with the aid of computer calculated dose distributions. Forty-three patients have been reviewed in order to ascertain the correlation between radiation injury and dose at reference points in the rectum and bladder. In a related study involving 77 patients, the doses at points A and B and the prescription in mghr were analyzed in relation to radiation injury. There was no apparent association between the incidence of radiation injury in either the mghr prescription or the doses at points A or B. Computer calculations were supplemented with in vivo and in vitro thermoluminescent dosimeter (TLD) measurements. We conclude that routine contrast radiography of the rectum and the bladder with dose calculations at selected reference points provides important information for optimizing radiotherapy in carcinoma of the cervix without a significant increase in treatment planning effort or patient discomfort.
Authors:
; ; ;
Publication Date:
OSTI Identifier:
6195487
Resource Type:
Conference
Resource Relation:
Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States); Journal Volume: 7:5; Conference: Annual meeting of the Radiological Society of North America, Atlanta, GA, USA, 24 Nov 1979
Research Org:
Pennsylvania State Univ., Hershey
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; BLADDER; DELAYED RADIATION EFFECTS; DIARRHEA; RADIOINDUCTION; ENTERITIS; FISTULAE; HEMORRHAGE; RADIOTHERAPY; RADIATION DOSES; SIDE EFFECTS; RECTUM; CARCINOMAS; CESIUM 137; FEMALE GENITALS; GAMMA RADIATION; ISODOSE CURVES; PATIENTS; RADIATION SOURCE IMPLANTS; THERMOLUMINESCENT DOSEMETERS; UROGENITAL SYSTEM DISEASES; X RADIATION; ALKALI METAL ISOTOPES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; CESIUM ISOTOPES; DIGESTIVE SYSTEM; DIGESTIVE SYSTEM DISEASES; DISEASES; DOSEMETERS; DOSES; ELECTROMAGNETIC RADIATION; GASTROINTESTINAL TRACT; IMPLANTS; INTESTINES; IONIZING RADIATIONS; ISOTOPES; LARGE INTESTINE; LUMINESCENT DOSEMETERS; MEASURING INSTRUMENTS; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANS; PATHOLOGICAL CHANGES; RADIATION EFFECTS; RADIATION SOURCES; RADIATIONS; RADIOISOTOPES; RADIOLOGY; SYMPTOMS; THERAPY; URINARY TRACT; YEARS LIVING RADIOISOTOPES 560151* -- Radiation Effects on Animals-- Man; 550603 -- Medicine-- External Radiation in Therapy-- (1980-); 550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)