Diagnosis and screening of small hepatocellular carcinomas: comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and. cap alpha. /sub 1/-fetoprotein assay
Abstract
Twenty-nine small (<5 cm) hepatocellular carcinomas in 18 patients were examined by radionuclide imaging (RN), ultrasound (US), computed tomography (CT), hepatic angiography, and serum ..cap alpha../sub 1/-fetoprotein (AFP) assay. Sensitivity was 39% with RN, 50% with US, 56% with CT, and 94% with angiography, including infusion hepatic angiography (IHA). Lesions larger than 3 cm could be detected by all of these methods; those between 2 and 3 cm were generally shown by US and CT but not RN. IHA was essential for diagnosis of lesions less than 2 cm, which were otherwise difficult or impossible to detect except with angiography. As a screening method, AFP was best, followed by US and CT. The authors recommend using AFP and US to minimize expense and radiation exposure. In questionable cases, IHA should be performed.
- Authors:
- Publication Date:
- Research Org.:
- Kanazawa Univ. School of Medicine, Japan
- OSTI Identifier:
- 6172929
- Resource Type:
- Journal Article
- Journal Name:
- Radiology; (United States)
- Additional Journal Information:
- Journal Volume: 145:3
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 62 RADIOLOGY AND NUCLEAR MEDICINE; CARCINOMAS; DIAGNOSIS; DIAGNOSTIC TECHNIQUES; COMPARATIVE EVALUATIONS; LIVER; BIOMEDICAL RADIOGRAPHY; COMPUTERIZED TOMOGRAPHY; SCINTISCANNING; ULTRASONOGRAPHY; BIOASSAY; ISOMERIC NUCLEI; PATIENTS; PROTEINS; RADIOCOLLOIDS; TECHNETIUM 99; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COLLOIDS; COUNTING TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; DISPERSIONS; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; RADIOLOGY; TECHNETIUM ISOTOPES; TOMOGRAPHY; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics; 550602 - Medicine- External Radiation in Diagnostics- (1980-)
Citation Formats
Takashima, T, Matsui, O, Suzuki, M, and Ida, M. Diagnosis and screening of small hepatocellular carcinomas: comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and. cap alpha. /sub 1/-fetoprotein assay. United States: N. p., 1982.
Web. doi:10.1148/radiology.145.3.6183708.
Takashima, T, Matsui, O, Suzuki, M, & Ida, M. Diagnosis and screening of small hepatocellular carcinomas: comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and. cap alpha. /sub 1/-fetoprotein assay. United States. https://doi.org/10.1148/radiology.145.3.6183708
Takashima, T, Matsui, O, Suzuki, M, and Ida, M. 1982.
"Diagnosis and screening of small hepatocellular carcinomas: comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and. cap alpha. /sub 1/-fetoprotein assay". United States. https://doi.org/10.1148/radiology.145.3.6183708.
@article{osti_6172929,
title = {Diagnosis and screening of small hepatocellular carcinomas: comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and. cap alpha. /sub 1/-fetoprotein assay},
author = {Takashima, T and Matsui, O and Suzuki, M and Ida, M},
abstractNote = {Twenty-nine small (<5 cm) hepatocellular carcinomas in 18 patients were examined by radionuclide imaging (RN), ultrasound (US), computed tomography (CT), hepatic angiography, and serum ..cap alpha../sub 1/-fetoprotein (AFP) assay. Sensitivity was 39% with RN, 50% with US, 56% with CT, and 94% with angiography, including infusion hepatic angiography (IHA). Lesions larger than 3 cm could be detected by all of these methods; those between 2 and 3 cm were generally shown by US and CT but not RN. IHA was essential for diagnosis of lesions less than 2 cm, which were otherwise difficult or impossible to detect except with angiography. As a screening method, AFP was best, followed by US and CT. The authors recommend using AFP and US to minimize expense and radiation exposure. In questionable cases, IHA should be performed.},
doi = {10.1148/radiology.145.3.6183708},
url = {https://www.osti.gov/biblio/6172929},
journal = {Radiology; (United States)},
number = ,
volume = 145:3,
place = {United States},
year = {Wed Dec 01 00:00:00 EST 1982},
month = {Wed Dec 01 00:00:00 EST 1982}
}