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Title: Diagnosis and screening of small hepatocellular carcinomas: comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and. cap alpha. /sub 1/-fetoprotein assay

Abstract

Twenty-nine small (<5 cm) hepatocellular carcinomas in 18 patients were examined by radionuclide imaging (RN), ultrasound (US), computed tomography (CT), hepatic angiography, and serum ..cap alpha../sub 1/-fetoprotein (AFP) assay. Sensitivity was 39% with RN, 50% with US, 56% with CT, and 94% with angiography, including infusion hepatic angiography (IHA). Lesions larger than 3 cm could be detected by all of these methods; those between 2 and 3 cm were generally shown by US and CT but not RN. IHA was essential for diagnosis of lesions less than 2 cm, which were otherwise difficult or impossible to detect except with angiography. As a screening method, AFP was best, followed by US and CT. The authors recommend using AFP and US to minimize expense and radiation exposure. In questionable cases, IHA should be performed.

Authors:
; ; ;
Publication Date:
Research Org.:
Kanazawa Univ. School of Medicine, Japan
OSTI Identifier:
6172929
Resource Type:
Journal Article
Journal Name:
Radiology; (United States)
Additional Journal Information:
Journal Volume: 145:3
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CARCINOMAS; DIAGNOSIS; DIAGNOSTIC TECHNIQUES; COMPARATIVE EVALUATIONS; LIVER; BIOMEDICAL RADIOGRAPHY; COMPUTERIZED TOMOGRAPHY; SCINTISCANNING; ULTRASONOGRAPHY; BIOASSAY; ISOMERIC NUCLEI; PATIENTS; PROTEINS; RADIOCOLLOIDS; TECHNETIUM 99; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COLLOIDS; COUNTING TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; DISPERSIONS; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; RADIOLOGY; TECHNETIUM ISOTOPES; TOMOGRAPHY; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics; 550602 - Medicine- External Radiation in Diagnostics- (1980-)

Citation Formats

Takashima, T, Matsui, O, Suzuki, M, and Ida, M. Diagnosis and screening of small hepatocellular carcinomas: comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and. cap alpha. /sub 1/-fetoprotein assay. United States: N. p., 1982. Web. doi:10.1148/radiology.145.3.6183708.
Takashima, T, Matsui, O, Suzuki, M, & Ida, M. Diagnosis and screening of small hepatocellular carcinomas: comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and. cap alpha. /sub 1/-fetoprotein assay. United States. https://doi.org/10.1148/radiology.145.3.6183708
Takashima, T, Matsui, O, Suzuki, M, and Ida, M. 1982. "Diagnosis and screening of small hepatocellular carcinomas: comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and. cap alpha. /sub 1/-fetoprotein assay". United States. https://doi.org/10.1148/radiology.145.3.6183708.
@article{osti_6172929,
title = {Diagnosis and screening of small hepatocellular carcinomas: comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and. cap alpha. /sub 1/-fetoprotein assay},
author = {Takashima, T and Matsui, O and Suzuki, M and Ida, M},
abstractNote = {Twenty-nine small (<5 cm) hepatocellular carcinomas in 18 patients were examined by radionuclide imaging (RN), ultrasound (US), computed tomography (CT), hepatic angiography, and serum ..cap alpha../sub 1/-fetoprotein (AFP) assay. Sensitivity was 39% with RN, 50% with US, 56% with CT, and 94% with angiography, including infusion hepatic angiography (IHA). Lesions larger than 3 cm could be detected by all of these methods; those between 2 and 3 cm were generally shown by US and CT but not RN. IHA was essential for diagnosis of lesions less than 2 cm, which were otherwise difficult or impossible to detect except with angiography. As a screening method, AFP was best, followed by US and CT. The authors recommend using AFP and US to minimize expense and radiation exposure. In questionable cases, IHA should be performed.},
doi = {10.1148/radiology.145.3.6183708},
url = {https://www.osti.gov/biblio/6172929}, journal = {Radiology; (United States)},
number = ,
volume = 145:3,
place = {United States},
year = {Wed Dec 01 00:00:00 EST 1982},
month = {Wed Dec 01 00:00:00 EST 1982}
}