Reconstruction of mandibular defects in irradiated patients

Journal Article · Mon Oct 01 00:00:00 EDT 1990 · American Journal of Surgery; (USA)

DOI:https://doi.org/10.1016/S0002-9610(05)80551-3· OSTI ID:6167985

Klotch, D W; Gump, J; Kuhn, L ^[1]

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1. Univ. of South Florida, Tampa (USA)

In this prospective study, mandibular reconstruction using titanium plates was evaluated in 31 patients treated between July 1988 and January 1990. Sixteen patients had prior surgery; 13 had prior radiotherapy. In 11 patients, prior radiation and surgery had failed. Sixteen patients received postoperative radiotherapy either in standard or accelerated fractions. Twelve patients had complications of either intraoral (8), extraoral (5), or combined (1) plate exposure or fistula formation (2). Factors significantly related to complications were poor nutrition, accelerated radiation, and recurrence. Sixty-one percent of all patients healed uneventfully. When patients with complications secondary to recurrence who subsequently died were excluded, the success rate was 73%. Only one patient had an unacceptable result that produced a cosmetic and functional deformity despite secondary repair.

• OSTI ID: 6167985
• Journal Information: American Journal of Surgery; (USA), Vol. 160:4; ISSN 0002-9610
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
FACE
BIOLOGICAL RADIATION EFFECTS
RADIOTHERAPY
SIDE EFFECTS
CARCINOMAS
ORAL CAVITY
OSTEORADIONECROSIS
PATIENTS
SKELETON
SKIN
SURGERY
TONGUE
BIOLOGICAL EFFECTS
BODY
BODY AREAS
DIGESTIVE SYSTEM
DISEASES
HEAD
INJURIES
LOCAL RADIATION EFFECTS
MEDICINE
NECROSIS
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIATION INJURIES
RADIOLOGY
SKELETAL DISEASES
THERAPY
560151* - Radiation Effects on Animals- Man