skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Salivary flow rates in patients with head and neck cancer 0. 5 to 25 years after radiotherapy

Journal Article · · Oral Surgery, Oral Medicine, Oral Pathology; (USA)
; ; ;  [1]
  1. Univ. of Texas, M.D. Anderson Cancer Center, Houston (USA)

In this clinical study at the University of Texas M. D. Anderson Cancer Center, unstimulated and stimulated salivary flow rates were obtained from 47 patients with head and neck cancer who had received mantle, unilateral facial, or bilateral facial field radiotherapy from 0.5 to 25 years earlier. The magnitude of salivary flow rate reduction compared with a healthy control group was primarily related to the radiation dosage and the amount of salivary gland tissue included in the irradiated fields. Flow rates were lower for women in all groups, but these differences were not statistically significant.

OSTI ID:
6144579
Journal Information:
Oral Surgery, Oral Medicine, Oral Pathology; (USA), Vol. 70:6; ISSN 0030-4220
Country of Publication:
United States
Language:
English

Similar Records

Analysis of Salivary Flow and Dose-Volume Modeling of Complication Incidence in Patients With Head-and-Neck Cancer Receiving Intensity-Modulated Radiotherapy
Journal Article · Sun Mar 15 00:00:00 EDT 2009 · International Journal of Radiation Oncology, Biology and Physics · OSTI ID:6144579

Impact of Salivary Gland Dosimetry on Post-IMRT Recovery of Saliva Output and Xerostomia Grade for Head-and-Neck Cancer Patients Treated With or Without Contralateral Submandibular Gland Sparing: A Longitudinal Study
Journal Article · Thu Dec 01 00:00:00 EST 2011 · International Journal of Radiation Oncology, Biology and Physics · OSTI ID:6144579

A Novel Dose Constraint to Reduce Xerostomia in Head-and-Neck Cancer Patients Treated With Intensity-Modulated Radiotherapy
Journal Article · Sat May 01 00:00:00 EDT 2010 · International Journal of Radiation Oncology, Biology and Physics · OSTI ID:6144579