Unique biological aspects of radiation hazards: an overview
The biological effects of HZE (high-Z energetic) particle radiation are discussed as they relate to the hazards of deep-space flight. The properties of HZE particles, generally defined as particles with atomic number 2 or greater and energy above 50 MeV/nucleon, are discussed, and the inapplicability of most common radiobiological measures, including rad doses and relative biological effectiveness, to HZE particles is pointed out. The microlesion concept is then presented as a meaningful measure of radiation damage due to HZE particles, and examples of studied microlesions are presented. A critical level for a microlesion event is suggested that corresponds to an ionization level with a high probability of inactivating the nucleus of a struck cell, and it is noted that HZE particles appear less effective in cell killing than gamma radiation. Future directions for studies of the effects of HZE particles on structures of the eye, development, the nervous system and carcinogenesis are indicated. 21 references.
- Research Organization:
- Pennsylvania State Univ., University Park, PA
- OSTI ID:
- 6131057
- Report Number(s):
- CONF-820582-
- Journal Information:
- Adv. Space Res.; (United States), Vol. 3; Conference: 24. COSPAR meeting (Committee on Space Research), Ottawa, Canada, 17 May 1982
- Country of Publication:
- United States
- Language:
- English
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