Mechanical properties of septal cartilage homografts

Journal Article · Sat Oct 01 00:00:00 EDT 1988 · Otolaryngol Head Neck Surg.; (United States)

DOI:https://doi.org/10.1177/019459988809900404· OSTI ID:6097648

Glasgold, M J; Kato, Y P; Christiansen, D; Hauge, J A; Glasgold, A I; Silver, F H

The compressive mechanical properties of untreated and chemically and physically treated nasal septum homografts were determined. Mechanical properties of control, saline-, thimerosal (Merthiolate)- and Alcide-treated specimens were similar. At high strains, the stiffness of treated cartilage ranged from 12.8 to 22.5 MPa and was unaffected by storage time. In comparison, irradiated and freeze-dried nasal septum exhibited stiffnesses of 35 and 37.5 MPa, respectively, after approximately 1 month of storage. These values of stiffness were significantly different from controls at a 0.95 confidence level. On the basis of these results, it was concluded that Alcide and Merthiolate treatment did not alter the compressive mechanical properties of cartilage and that a combination of these treatments may adequately sterilize and preserve nasal septum homografts.

• Research Organization: UMDNJ-Robert Wood Johnson Medical School, Piscataway (USA)
• OSTI ID: 6097648
• Journal Information: Otolaryngol Head Neck Surg.; (United States), Vol. 99:4
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CARTILAGE
MECHANICAL PROPERTIES
GRAFTS
STORAGE LIFE
DRYING
ELASTICITY
FREEZING
IN VITRO
NOSE
RADIOPRESERVATION
SODIUM CHLORIDES
ALKALI METAL COMPOUNDS
ANIMAL TISSUES
BODY
BODY AREAS
CHLORIDES
CHLORINE COMPOUNDS
CONNECTIVE TISSUE
FACE
HALIDES
HALOGEN COMPOUNDS
HEAD
IRRADIATION
PRESERVATION
RESPIRATORY SYSTEM
SODIUM COMPOUNDS
TENSILE PROPERTIES
TISSUES
TRANSPLANTS
560120* - Radiation Effects on Biochemicals
Cells
& Tissue Culture