skip to main content

Title: Segmental irradiation of the bladder with neodymium YAG laser irradiation

The Neodymium YAG laser energy source can be readily adapted for cystoscopic use by some simple modifications of existing urologic equipment. Both the fiberoptic resectoscope and a deflecting cystourethroscope have been adapted for this purpose. Fixation of the fiber tip 1 cm. from the target and use of a divergent beam of 36 degrees allows the delivery of standardized dosage to a relatively large bladder tissue volume. Animal experiments involving 35 mongrel dogs established that repetitive overlapping doses of 200 joules ech can successfully treat a large area of bladder resulting in a full thickness bladder wall injury. This technique has been used in 4 high risk patients with infiltrating bladder cancer without adverse sequelae. The ability to reliably produce a full thickness lesion may give this modality a therapeutic advantage over conventional cautery techniques especially for the treatment of residual infiltrative carcinoma.
Authors:
; ; ; ; ;
Publication Date:
OSTI Identifier:
6096530
Resource Type:
Journal Article
Resource Relation:
Journal Name: J. Urol.; (United States); Journal Volume: 128:5
Research Org:
Department of Surgery (Urology), University of Alberta, Edmonton, Canada
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BLADDER; LOCAL IRRADIATION; NEODYMIUM LASERS; PERFORMANCE; USES; NEOPLASMS; RADIOTHERAPY; COMPARATIVE EVALUATIONS; DOGS; NEODYMIUM; RADIATION DOSES; RADIOSENSITIVITY; THICKNESS; USA; ANIMALS; BODY; DIMENSIONS; DISEASES; DOSES; ELEMENTS; IRRADIATION; LASERS; MAMMALS; MEDICINE; METALS; NORTH AMERICA; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; RARE EARTHS; SOLID STATE LASERS; THERAPY; URINARY TRACT; VERTEBRATES 550603* -- Medicine-- External Radiation in Therapy-- (1980-)