Segmental irradiation of the bladder with neodymium YAG laser irradiation

Journal Article · Mon Nov 01 00:00:00 EST 1982 · J. Urol.; (United States)

OSTI ID:6096530

McPhee, M S; Mador, D R; Tulip, J; Ritchie, B; Moore, R; Lakey, W H

The Neodymium YAG laser energy source can be readily adapted for cystoscopic use by some simple modifications of existing urologic equipment. Both the fiberoptic resectoscope and a deflecting cystourethroscope have been adapted for this purpose. Fixation of the fiber tip 1 cm. from the target and use of a divergent beam of 36 degrees allows the delivery of standardized dosage to a relatively large bladder tissue volume. Animal experiments involving 35 mongrel dogs established that repetitive overlapping doses of 200 joules ech can successfully treat a large area of bladder resulting in a full thickness bladder wall injury. This technique has been used in 4 high risk patients with infiltrating bladder cancer without adverse sequelae. The ability to reliably produce a full thickness lesion may give this modality a therapeutic advantage over conventional cautery techniques especially for the treatment of residual infiltrative carcinoma.

• Research Organization: Department of Surgery (Urology), University of Alberta, Edmonton, Canada
• OSTI ID: 6096530
• Journal Information: J. Urol.; (United States), Vol. 128:5
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BLADDER
LOCAL IRRADIATION
NEODYMIUM LASERS
PERFORMANCE
USES
NEOPLASMS
RADIOTHERAPY
COMPARATIVE EVALUATIONS
DOGS
NEODYMIUM
RADIATION DOSES
RADIOSENSITIVITY
THICKNESS
USA
ANIMALS
BODY
DIMENSIONS
DISEASES
DOSES
ELEMENTS
IRRADIATION
LASERS
MAMMALS
MEDICINE
METALS
NORTH AMERICA
NUCLEAR MEDICINE
ORGANS
RADIOLOGY
RARE EARTHS
SOLID STATE LASERS
THERAPY
URINARY TRACT
VERTEBRATES
550603* - Medicine- External Radiation in Therapy- (1980-)