Splenic imaging in a patient with functional asplenia

Journal Article · Sat Apr 01 00:00:00 EST 1989 · Clin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1097/00003072-198904000-00005· OSTI ID:6078624

Wagman, P G; Dworkin, H J

A 65-year-old woman presented with right upper extremity paralysis and left cerebrovascular accident. A routine complete blood count (CBC) demonstrated Howell-Jolly bodies on peripheral smear, and a liver-spleen scan showed absent splenic sulfur colloid uptake suggesting functional asplenia. A subsequent heat damaged red blood cell study demonstrated a normal sized spleen with preserved sequestering function, thereby excluding anatomic asplenia, vascular alterations, or congenital anomalies in the differential diagnosis of functional asplenia. This case illustrates the use of Tc-99m heat damaged red blood cells as a unique and useful diagnostic aid in identifying the presence and size of a spleen in patients with functional asplenia. It also demonstrates an apparent qualitative separation of splenic functions in processing sulfur colloid and heat damaged red blood cells.

• Research Organization: William Beaumont Hospital, Royal Oak, MI (USA)
• OSTI ID: 6078624
• Journal Information: Clin. Nucl. Med.; (United States), Vol. 14:4
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
SPLEEN
RADIOISOTOPE SCANNING
VASCULAR DISEASES
DIAGNOSIS
COLLOIDS
ERYTHROCYTES
HEAT
ISOMERIC NUCLEI
PATIENTS
RETICULOENDOTHELIAL SYSTEM
TECHNETIUM 99
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
COUNTING TECHNIQUES
DISEASES
DISPERSIONS
ENERGY
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
TECHNETIUM ISOTOPES
TISSUES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics