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Title: Extremely low frequency pulsed electromagnetic fields increase cell proliferation in lymphocytes from young and aged subjects

The effect of the in vitro exposure to extremely low frequency pulsed electromagnetic fields (PEMFs) on the proliferation of human lymphocytes from 24 young and 24 old subjects was studied. The exposure to PEMFs during a 3-days culture period or during the first 24 hours was able to increase phytohaemagglutinin-induced lymphocyte proliferation in both groups. Such effect was greater in lymphocytes from old people which showed a markedly reduced proliferative capability and, after PEMF exposure, reached values of /sup 3/H-TdR incorporation similar to those of young subjects. The relevance of these data for the understanding and the reversibility of the proliferative defects in cells from aged subjects and for the assessment of risk related to the environmental exposure to PEMFs has to be considered.
Authors:
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Publication Date:
OSTI Identifier:
6070250
Resource Type:
Journal Article
Resource Relation:
Journal Name: Biochem. Biophys. Res. Commun.; (United States); Journal Volume: 160:2
Research Org:
Univ. of Modena (Italy)
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; ELECTROMAGNETIC FIELDS; BIOLOGICAL EFFECTS; LYMPHOCYTES; CELL PROLIFERATION; AGE DEPENDENCE; CELL CULTURES; MAN; PHYTOHEMAGGLUTININ; THYMIDINE; TRACER TECHNIQUES; TRITIUM COMPOUNDS; AGGLUTININS; ANIMAL CELLS; ANIMALS; ANTIBODIES; AZINES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CARBOHYDRATES; CONNECTIVE TISSUE CELLS; HEMAGGLUTININS; HETEROCYCLIC COMPOUNDS; ISOTOPE APPLICATIONS; LABELLED COMPOUNDS; LEUKOCYTES; MAMMALS; MATERIALS; MITOGENS; MUCOPROTEINS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; POLYSACCHARIDES; PRIMATES; PROTEINS; PYRIMIDINES; RIBOSIDES; SACCHARIDES; SOMATIC CELLS; VERTEBRATES 560400* -- Other Environmental Pollutant Effects; 550201 -- Biochemistry-- Tracer Techniques