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Title: Effect of hydrogen fluoride inhalation on lipid metabolism in guinea pigs

Abstract

The action of fluoride in vivo (exposure 96 hrs to 7 mg/m3) on the metabolism of cyclic AMP and relationship between cAMP and lipid metabolism was investigated. The mean values for cAMP, non esterified fatty acids and cholesterol were significantly increased after hydrogen fluoride exposure. cAMP is directly responsible for the increased lipolysis. In animals exposed to HF, theophylline injection causes increases of non esterified fatty acids and not produces modification of cholesterol level.

Authors:
; ; ;  [1]
  1. Department of Toxicology, Faculte de Pharmacie, Toulouse (France)
Publication Date:
OSTI Identifier:
5996208
Resource Type:
Journal Article
Journal Name:
Artery (Fulton, Michigan); (United States)
Additional Journal Information:
Journal Volume: 18:5; Journal ID: ISSN 0098-6127
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; HYDROFLUORIC ACID; BIOLOGICAL EFFECTS; LIPIDS; METABOLISM; AMP; CHOLESTEROL; GUINEA PIGS; INHALATION; MAXIMUM PERMISSIBLE EXPOSURE; ANIMALS; FLUORINE COMPOUNDS; HALOGEN COMPOUNDS; HYDROGEN COMPOUNDS; HYDROXY COMPOUNDS; INORGANIC ACIDS; INTAKE; MAMMALS; NUCLEOTIDES; ORGANIC COMPOUNDS; RODENTS; SAFETY STANDARDS; STANDARDS; STEROIDS; STEROLS; VERTEBRATES; 560300* - Chemicals Metabolism & Toxicology

Citation Formats

Philibert, C, Dousset, J C, Rioufol, C, and Bourbon, P. Effect of hydrogen fluoride inhalation on lipid metabolism in guinea pigs. United States: N. p., 1991. Web.
Philibert, C, Dousset, J C, Rioufol, C, & Bourbon, P. Effect of hydrogen fluoride inhalation on lipid metabolism in guinea pigs. United States.
Philibert, C, Dousset, J C, Rioufol, C, and Bourbon, P. 1991. "Effect of hydrogen fluoride inhalation on lipid metabolism in guinea pigs". United States.
@article{osti_5996208,
title = {Effect of hydrogen fluoride inhalation on lipid metabolism in guinea pigs},
author = {Philibert, C and Dousset, J C and Rioufol, C and Bourbon, P},
abstractNote = {The action of fluoride in vivo (exposure 96 hrs to 7 mg/m3) on the metabolism of cyclic AMP and relationship between cAMP and lipid metabolism was investigated. The mean values for cAMP, non esterified fatty acids and cholesterol were significantly increased after hydrogen fluoride exposure. cAMP is directly responsible for the increased lipolysis. In animals exposed to HF, theophylline injection causes increases of non esterified fatty acids and not produces modification of cholesterol level.},
doi = {},
url = {https://www.osti.gov/biblio/5996208}, journal = {Artery (Fulton, Michigan); (United States)},
issn = {0098-6127},
number = ,
volume = 18:5,
place = {United States},
year = {Tue Jan 01 00:00:00 EST 1991},
month = {Tue Jan 01 00:00:00 EST 1991}
}