Localized 1H NMR spectroscopy in fifty cases of newly diagnosed intracranial tumors

Journal Article · Tue Jan 01 00:00:00 EST 1991 · Journal of Computer Assisted Tomography; (USA)

DOI:https://doi.org/10.1097/00004728-199101000-00009· OSTI ID:5987917

Demaerel, P; Johannik, K; Van Hecke, P; Van Ongeval, C; Verellen, S; Marchal, G; Wilms, G; Plets, C; Goffin, J; Van Calenbergh, F ^[1]

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1. Univ. Hospitals K.U. Leuven (Belgium)

Fifty patients with newly diagnosed, untreated intracranial tumors were examined with 1H nuclear magnetic resonance single-volume spectroscopy (MRS) using a 1.5 T whole-body MR system. Prior to the MRS, contrast enhanced MR and/or CT imaging studies were carried out. Histological verification was obtained in all patients except one. All tumor spectra revealed distinct abnormalities as compared with the normal brain spectra. Although most meningiomas showed a rather characteristic spectral pattern, generally features specific for the various tumor types were not observed. For instance, though a strong lactic acid signal was seen in most malignant tumors, this signal was also evident in five benign neoplasms.

• OSTI ID: 5987917
• Journal Information: Journal of Computer Assisted Tomography; (USA), Vol. 15:1; ISSN 0363-8715
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BRAIN
NEOPLASMS
DIAGNOSIS
NMR IMAGING
SENSITIVITY ANALYSIS
LACTIC ACID
NUCLEAR MAGNETIC RESONANCE
PATIENTS
PROTONS
BARYONS
BODY
CARBOXYLIC ACIDS
CENTRAL NERVOUS SYSTEM
DIAGNOSTIC TECHNIQUES
DISEASES
ELEMENTARY PARTICLES
FERMIONS
HADRONS
HYDROXY ACIDS
MAGNETIC RESONANCE
NERVOUS SYSTEM
NUCLEONS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
RESONANCE
550600* - Medicine