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Title: Idiopathic interstitial pneumonia following bone marrow transplantation: the relationship with total body irradiation

Abstract

Interstitial pneumonia is a frequent and often fatal complication of allogenic bone marrow transplantation. Thirty to 40 percent of such cases are of unknown etiology and have been labelled as cases of idiopathic interstitial pneumonia. Idiopathic cases are more commonly associated with the use of total body irradiation; their occurrence appears to be independent of immunosupression or graft versus host disease. Evidence is presented from the literature suggesting that the development of idiopathic interstitial pneumonia is related to the absolute absorbed dose of radiation to lung. The similarity of idiopathic pneumonia to radiation pneumonitis seen in a different clinical setting is described.

Authors:
; ;
Publication Date:
Research Org.:
Ontario Cancer Inst., Toronto, Canada
OSTI Identifier:
5923609
Resource Type:
Journal Article
Journal Name:
Int. J. Radiat. Oncol., Biol. Phys.; (United States)
Additional Journal Information:
Journal Volume: 7:10
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BONE MARROW; TRANSPLANTS; WHOLE-BODY IRRADIATION; SIDE EFFECTS; GRAFT-HOST REACTION; IMMUNOSUPPRESSION; PNEUMONIA; RADIATION DOSES; RADIOTHERAPY; ANIMAL TISSUES; BODY; DISEASES; DOSES; EXTERNAL IRRADIATION; HEMATOPOIETIC SYSTEM; IRRADIATION; MEDICINE; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; RESPIRATORY SYSTEM DISEASES; THERAPY; TISSUES; 550603* - Medicine- External Radiation in Therapy- (1980-)

Citation Formats

Keane, T J, Van Dyk, J, and Rider, W D. Idiopathic interstitial pneumonia following bone marrow transplantation: the relationship with total body irradiation. United States: N. p., 1981. Web. doi:10.1016/0360-3016(81)90032-8.
Keane, T J, Van Dyk, J, & Rider, W D. Idiopathic interstitial pneumonia following bone marrow transplantation: the relationship with total body irradiation. United States. https://doi.org/10.1016/0360-3016(81)90032-8
Keane, T J, Van Dyk, J, and Rider, W D. 1981. "Idiopathic interstitial pneumonia following bone marrow transplantation: the relationship with total body irradiation". United States. https://doi.org/10.1016/0360-3016(81)90032-8.
@article{osti_5923609,
title = {Idiopathic interstitial pneumonia following bone marrow transplantation: the relationship with total body irradiation},
author = {Keane, T J and Van Dyk, J and Rider, W D},
abstractNote = {Interstitial pneumonia is a frequent and often fatal complication of allogenic bone marrow transplantation. Thirty to 40 percent of such cases are of unknown etiology and have been labelled as cases of idiopathic interstitial pneumonia. Idiopathic cases are more commonly associated with the use of total body irradiation; their occurrence appears to be independent of immunosupression or graft versus host disease. Evidence is presented from the literature suggesting that the development of idiopathic interstitial pneumonia is related to the absolute absorbed dose of radiation to lung. The similarity of idiopathic pneumonia to radiation pneumonitis seen in a different clinical setting is described.},
doi = {10.1016/0360-3016(81)90032-8},
url = {https://www.osti.gov/biblio/5923609}, journal = {Int. J. Radiat. Oncol., Biol. Phys.; (United States)},
number = ,
volume = 7:10,
place = {United States},
year = {Thu Oct 01 00:00:00 EDT 1981},
month = {Thu Oct 01 00:00:00 EDT 1981}
}