skip to main content

Title: Concentration and chemical status of arsenic in the early placentas of arsenate-dosed hamsters

The authors determined the concentration and chemical status of arsenic in the placentas of hamsters following continuous exposure via the osmotic minipump to minimally and frankly teratogenic doses of arsenate. Close to 70% of the placental arsenic is bound to macromolecules, two-thirds of which is dialyzable. The remaining 30% of arsenic consists of low molecular weight species, predominantly inorganic arsenic. This mix is the same for minimally teratogenic and frankly teratogenic doses of arsenate.
Authors:
;
Publication Date:
OSTI Identifier:
5897429
Resource Type:
Journal Article
Resource Relation:
Journal Name: Environ. Res.; (United States); Journal Volume: 42:2
Research Org:
Dartmouth Medical School, Hanover, NH
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ARSENIC; BIOLOGICAL ACCUMULATION; CHEMICAL STATE; MEMBRANE TRANSPORT; FETAL MEMBRANES; HAMSTERS; TERATOGENESIS; ANIMALS; ELEMENTS; MAMMALS; MEMBRANES; RODENTS; SEMIMETALS; VERTEBRATES 560300* -- Chemicals Metabolism & Toxicology