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Title: Qualitative evaluation of coronary flow during anesthetic induction using thallium-201 perfusion scans

Abstract

Qualitative distribution of coronary flow using thallium-201 perfusion scans immediately postintubation was studied in 22 patients scheduled for elective coronary artery bypass surgery. Ten patients received a thiopental (4 mg/kg) and halothane induction. Twelve patients received a fentanyl (100 micrograms/kg) induction. Baseline thallium-201 perfusion scans were performed 24 h prior to surgery. These scans were compared with the scans performed postintubation. A thallium-positive scan was accepted as evidence of relative hypoperfusion. Baseline hemodynamic and ECG data were obtained prior to induction of anesthesia. These data were compared with the data obtained postintubation. Ten patients developed postintubation thallium-perfusion scan defects (thallium-positive scan), even though there was no statistical difference between their baseline hemodynamics and hemodynamics at the time of intubation. There was no difference in the incidence of thallium-positive scans between those patients anesthetized by fentanyl and those patients anesthetized with thiopental-halothane. The authors conclude that relative hypoperfusion, and possibly ischemia, occurred in 45% of patients studied, despite stable hemodynamics, and that the incidence of these events was the same with two different anesthetic techniques.

Authors:
; ; ; ; ; ; ;
Publication Date:
Research Org.:
Loyola Univ. Stritch School of Medicine, Maywood, IL
OSTI Identifier:
5883198
Resource Type:
Journal Article
Journal Name:
Anesthesiology; (United States)
Additional Journal Information:
Journal Volume: 2
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CORONARIES; SCINTISCANNING; HEART; BLOOD FLOW; ANESTHESIA; ISCHEMIA; MONITORING; PATIENTS; PERFUSED ORGANS; SURGERY; THALLIUM 201; THIOPENTAL; ANESTHETICS; ARTERIES; AZINES; BARBITURATES; BETA DECAY RADIOISOTOPES; BLOOD VESSELS; BODY; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM DEPRESSANTS; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; HEAVY NUCLEI; HETEROCYCLIC COMPOUNDS; HYPNOTICS AND SEDATIVES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANIC OXYGEN COMPOUNDS; ORGANIC SULFUR COMPOUNDS; ORGANS; PYRIMIDINES; RADIOISOTOPE SCANNING; RADIOISOTOPES; SECONDS LIVING RADIOISOTOPES; THALLIUM ISOTOPES; VASCULAR DISEASES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats

Kleinman, B, Henkin, R E, Glisson, S N, el-Etr, A A, Bakhos, M, Sullivan, H J, Montoya, A, and Pifarre, R. Qualitative evaluation of coronary flow during anesthetic induction using thallium-201 perfusion scans. United States: N. p., 1986. Web. doi:10.1097/00000542-198602000-00005.
Kleinman, B, Henkin, R E, Glisson, S N, el-Etr, A A, Bakhos, M, Sullivan, H J, Montoya, A, & Pifarre, R. Qualitative evaluation of coronary flow during anesthetic induction using thallium-201 perfusion scans. United States. https://doi.org/10.1097/00000542-198602000-00005
Kleinman, B, Henkin, R E, Glisson, S N, el-Etr, A A, Bakhos, M, Sullivan, H J, Montoya, A, and Pifarre, R. 1986. "Qualitative evaluation of coronary flow during anesthetic induction using thallium-201 perfusion scans". United States. https://doi.org/10.1097/00000542-198602000-00005.
@article{osti_5883198,
title = {Qualitative evaluation of coronary flow during anesthetic induction using thallium-201 perfusion scans},
author = {Kleinman, B and Henkin, R E and Glisson, S N and el-Etr, A A and Bakhos, M and Sullivan, H J and Montoya, A and Pifarre, R},
abstractNote = {Qualitative distribution of coronary flow using thallium-201 perfusion scans immediately postintubation was studied in 22 patients scheduled for elective coronary artery bypass surgery. Ten patients received a thiopental (4 mg/kg) and halothane induction. Twelve patients received a fentanyl (100 micrograms/kg) induction. Baseline thallium-201 perfusion scans were performed 24 h prior to surgery. These scans were compared with the scans performed postintubation. A thallium-positive scan was accepted as evidence of relative hypoperfusion. Baseline hemodynamic and ECG data were obtained prior to induction of anesthesia. These data were compared with the data obtained postintubation. Ten patients developed postintubation thallium-perfusion scan defects (thallium-positive scan), even though there was no statistical difference between their baseline hemodynamics and hemodynamics at the time of intubation. There was no difference in the incidence of thallium-positive scans between those patients anesthetized by fentanyl and those patients anesthetized with thiopental-halothane. The authors conclude that relative hypoperfusion, and possibly ischemia, occurred in 45% of patients studied, despite stable hemodynamics, and that the incidence of these events was the same with two different anesthetic techniques.},
doi = {10.1097/00000542-198602000-00005},
url = {https://www.osti.gov/biblio/5883198}, journal = {Anesthesiology; (United States)},
number = ,
volume = 2,
place = {United States},
year = {Sat Feb 01 00:00:00 EST 1986},
month = {Sat Feb 01 00:00:00 EST 1986}
}