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Title: Structure of amphotericin B aggregates based on calculations of optical spectra

Journal Article · · Biopolymers; (United States)

The degenerate ground state approximation was used to calculate the optical absorption and CD spectra for helical polymer models of amphotericin B aggregates in aqueous solution. Comparisons with experimental spectra indicate that a two-molecule/unit cell helical polymer model is a possible structure for aggregates of amphotericin B.

Research Organization:
Southern California College of Optometry, Fullerton
DOE Contract Number:
W-7405-ENG-26
OSTI ID:
5864065
Journal Information:
Biopolymers; (United States), Vol. 22
Country of Publication:
United States
Language:
English