Animal bioavailability of defined xenobiotic lignin metabolites

Journal Article · Sat Sep 01 00:00:00 EDT 1990 · Journal of Agricultural and Food Chemistry; (USA)

DOI:https://doi.org/10.1021/jf00099a020· OSTI ID:5837029

Sandermann, H Jr; Arjmand, M; Gennity, I; Winkler, R ^[1]; Struble, C B; Aschbacher, P W ^[2]

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1. Institut fuer Biochemische Pflanzenpathologie, Neuherberg (West Germany)
2. Department of Agriculture, Fargo, ND (USA)

Lignin has been recognized as a major component of bound pesticide residues in plants and is thought to be undigestible in animals. Two defined ring-U-{sup 14}C-labeled chloroaniline/lignin metabolites have now been fed to rats, where a release of {approximately}66% of the bound xenobiotic occurred in the form of simple chloroaniline derivatives. The observed high degree of bioavailability indicates that bound pesticidal residues may possess ecotoxicological significance. In parallel studies, the white-rot fungus Phanerochaete chrysosporium was more efficient, and a soil system was much less efficient, in the degradation of the (ring-U-{sup 14}C)chloroaniline/lignin metabolites.

• OSTI ID: 5837029
• Journal Information: Journal of Agricultural and Food Chemistry; (USA), Vol. 38:9; ISSN 0021-8561
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
54 ENVIRONMENTAL SCIENCES
PESTICIDES
BIOLOGICAL AVAILABILITY
BIODEGRADATION
CARBON 14 COMPOUNDS
FUNGI
LIGNIN
METABOLISM
METABOLITES
RATS
SOILS
TRACER TECHNIQUES
ANIMALS
CARBOHYDRATES
CHEMICAL REACTIONS
DECOMPOSITION
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
MAMMALS
ORGANIC COMPOUNDS
PLANTS
POLYSACCHARIDES
RODENTS
SACCHARIDES
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology
540211 - Environment
Terrestrial- Basic Studies- Radiometric Techniques- (1990-)