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Title: Pertechnetate and the stomach: a continuing controversy

Abstract

Technetium-99m is concentrated by the stomach following intravenous injection. This principle allows the detection of ectopic gastric mucosa and has been used to develop a noninvasive test of gastric secretion. The cellular site of concentration is controversial, however, with evidence implicating both the acid-secreting parietal cells, and the mucus secreting epithelial cells of the gastric mucosa. This evidence is reviewed and appraised. It is suggested that the primary mechanism lies in the muccous cell but that total gastric activity following pertechnetate reflects the health, surface area, and blood flow of the mucous epithelium.

Authors:
Publication Date:
Research Org.:
Royal Naval Hospital, Plymouth, England
OSTI Identifier:
5821462
Resource Type:
Journal Article
Journal Name:
J. Nucl. Med.; (United States)
Additional Journal Information:
Journal Volume: 24:7
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; PERTECHNETATES; CHEMICAL PROPERTIES; STOMACH; SCINTISCANNING; TECHNETIUM 99; BLOOD FLOW; EPITHELIUM; INTRAVENOUS INJECTION; ISOMERIC NUCLEI; MUCOUS MEMBRANES; ANIMAL TISSUES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; GASTROINTESTINAL TRACT; HOURS LIVING RADIOISOTOPES; INJECTION; INTAKE; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEMBRANES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; OXYGEN COMPOUNDS; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM COMPOUNDS; TECHNETIUM ISOTOPES; TISSUES; TRANSITION ELEMENT COMPOUNDS; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics; 400702 - Radiochemistry & Nuclear Chemistry- Properties of Radioactive Materials

Citation Formats

Williams, J G. Pertechnetate and the stomach: a continuing controversy. United States: N. p., 1983. Web.
Williams, J G. Pertechnetate and the stomach: a continuing controversy. United States.
Williams, J G. 1983. "Pertechnetate and the stomach: a continuing controversy". United States.
@article{osti_5821462,
title = {Pertechnetate and the stomach: a continuing controversy},
author = {Williams, J G},
abstractNote = {Technetium-99m is concentrated by the stomach following intravenous injection. This principle allows the detection of ectopic gastric mucosa and has been used to develop a noninvasive test of gastric secretion. The cellular site of concentration is controversial, however, with evidence implicating both the acid-secreting parietal cells, and the mucus secreting epithelial cells of the gastric mucosa. This evidence is reviewed and appraised. It is suggested that the primary mechanism lies in the muccous cell but that total gastric activity following pertechnetate reflects the health, surface area, and blood flow of the mucous epithelium.},
doi = {},
url = {https://www.osti.gov/biblio/5821462}, journal = {J. Nucl. Med.; (United States)},
number = ,
volume = 24:7,
place = {United States},
year = {Fri Jul 01 00:00:00 EDT 1983},
month = {Fri Jul 01 00:00:00 EDT 1983}
}