Cadmium kinetics in freshwater clams. Uptake of cadmium by the excised gill of Anodonta anatina

Journal Article · Wed Mar 01 00:00:00 EST 1989 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01699964· OSTI ID:5815135

Holwerda, D A; de Knecht, J A; Hemelraad, J; Veenhof, P R

There are several, and sometimes conflicting, reports on metal interaction during bioaccumulation from a mixture of heavy metals by marine or estuarine organisms. Concerning the influence of zinc on Cd uptake, it was found in a previous study with the freshwater clam Anodonta cygnea that zinc retarded the accumulation of cadmium when present in a hundred-fold excess over the latter metal. In the only in vitro investigation known, it was shown that the uptake of cadmium by the excised gills of the seal mussel Mytilus edulis was not affected by co-exposure with other metal ions or by the presence of metabolic inhibitors. By contrast, bioaccumulation of cadmium in M. edulis was strongly reduced by co-exposure to zinc in a hundred-fold excess over cadmium. The clear effect of zinc on Cd accumulation in A. cygnea prompted the authors to investigate this phenomenon in an in vitro model. The primary aim was to detect whether the in vivo effect of zinc is caused by a direct influence on the gill epithelium or is sustained by a behavioral response of the animal. At the same time, the possible effect of some other exogenous factors on Cd uptake was examined. In addition, it was investigated whether the rate of in vitro uptake is a function of gill size.

• Research Organization: Univ. of Utrecht (Netherlands)
• OSTI ID: 5815135
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Vol. 42:3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CADMIUM COMPOUNDS
BIOCHEMICAL REACTION KINETICS
ZINC COMPOUNDS
BIOLOGICAL EFFECTS
CLAMS
EPITHELIUM
GILLS
IN VITRO
METABOLISM
ANIMAL TISSUES
ANIMALS
AQUATIC ORGANISMS
BODY
INVERTEBRATES
KINETICS
MOLLUSCS
REACTION KINETICS
RESPIRATORY SYSTEM
TISSUES
560300* - Chemicals Metabolism & Toxicology