Radiation absorbed doses from iron-52, iron-55, and iron-59 used to study ferrokinetics
Biological data obtained principally with Fe-59 citrate are used with physical data to calculate radiation absorbed doses for ionic or weak chelate forms of Fe-52, Fe-55, and Fe-59, administered by intravenous injection. Doses are calculated for normal subjects, primary hemochromatosis (also called idiopathic or hereditary hemochromatosis), pernicious anemia in relapse, iron-deficiency anemia, and polycythemia vera. The Fe-52 doses include the dose from the Mn-52m daughter generated after injection of Fe-52. Special attention has been given to the dose to the spleen, which has a relatively high concentration of RBCs and therefore of radioiron, and which varies significantly in size in both health and disease.
- Research Organization:
- Diagnostic Nuclear Medicine, Mayo Clinic, Rochester, MN
- OSTI ID:
- 5762122
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 24:4
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
IRON 52
UPTAKE
IRON 55
IRON 59
CALCULATION METHODS
CITRATES
ERYTHROCYTES
HEMIC DISEASES
INTRAVENOUS INJECTION
MAN
RADIATION DOSES
RADIONUCLIDE KINETICS
SPLEEN
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
CARBOXYLIC ACID SALTS
DAYS LIVING RADIOISOTOPES
DISEASES
DOSES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-EVEN NUCLEI
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
INJECTION
INTAKE
INTERMEDIATE MASS NUCLEI
IRON ISOTOPES
ISOTOPES
MAMMALS
MATERIALS
NUCLEI
ORGANS
PRIMATES
RADIOISOTOPES
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560171* - Radiation Effects- Nuclide Kinetics & Toxicology- Man- (-1987)