Effects of ambient ozone on respiratory function and symptoms in Mexico City schoolchildren
- Universidad Autonoma Metropolitana-X, Mexico City, (Mexico)
The effects of ambient ozone (O3) on respiratory function and acute respiratory symptoms were evaluated in 143 7- to 9-yr-old schoolchildren followed longitudinally at 1- to 2-wk intervals over a period of 6 months at three schools in Pedregal, Mexico City. The maximum O3 level exceeded the World Health Organization guideline of 80 ppb and the U.S. standard of 120 ppb in every week. For an increase from lowest to highest in the mean O3 level during the 48 hr before spirometry (53 ppb), logistic regression estimated relative odds of 1.7 for a child reporting cough/phlegm on the day of spirometry. For the full population, the mean O3 level during the hour before spirometry, not adjusted for temperature and humidity, predicted a significant decrement in FVC but not in FEV1 or FEF25-75. In contrast, the mean O3 level during the previous 24-, 48-, and 168-h periods predicted significant decrements in FEV1 and FEF25-75 but not in FVC. Ozone was consistently associated with a greater decrement in lung function for the 15 children with chronic phlegm as compared with the children without chronic cough, chronic phlegm, or wheeze. Ozone in the previous 24-, 48-, and 168-h periods predicted decrements in FEV1 for children of mothers who were current or former smokers, but not for children of mothers who were never smokers. Many of these effects were reduced in multiple regression analyses including temperature and humidity, as temperature and O3 were highly correlated.
- OSTI ID:
- 5747245
- Journal Information:
- American Review of Respiratory Disease (New York); (United States), Vol. 145:2 Pt 1; ISSN 0003-0805
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
MEXICO
AIR POLLUTION
OZONE
TOXICITY
RESPIRATORY SYSTEM
SENSITIVITY
AIR POLLUTION MONITORING
CHILDREN
ECOLOGICAL CONCENTRATION
REGRESSION ANALYSIS
RESPIRATORY SYSTEM DISEASES
SYMPTOMS
AGE GROUPS
DEVELOPING COUNTRIES
DISEASES
LATIN AMERICA
MATHEMATICS
MONITORING
NORTH AMERICA
POLLUTION
STATISTICS
540120* - Environment
Atmospheric- Chemicals Monitoring & Transport- (1990-)
560300 - Chemicals Metabolism & Toxicology