Dioxins and dibenzofurans in adipose tissue of U. S. Vietnam veterans and controls
Concern about the adverse effects of exposure to Agent Orange is for the most part attributable to its toxic contaminant, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). A total of 40 Vietnam veterans, 80 non-Vietnam veterans and 80 civilian men were selected from males born between 1936 and 1954 and their adipose tissues were analyzed for 17 2,3,7,8-substituted dioxins and dibenzofurans. TCDD levels were log normally distributed and the mean level of 2,3,7,8-TCDD in adipose tissue of the Vietnam veterans (13.4 ppt) was not significantly different from that of the non-Vietnam veterans (12.5 ppt) or civilian men (15.8 ppt). Adjusting for demographic variables did not change the conclusions. The study results suggest that heavy exposure to Agent Orange for most Vietnam veterans was very unlikely and that there is no readily available and reliable indirect method of assessing exposure to Agent Orange for Vietnam veterans.
- Research Organization:
- Environmental Protection Agency, Washington, DC (USA). Office of Toxic Substances
- OSTI ID:
- 5732431
- Report Number(s):
- PB-91-167585/XAB; EPA-560/5-89/002
- Resource Relation:
- Other Information: Prepared in cooperation with Department of Veterans Affairs, Washington, DC. Office of Environmental Epidemiology, Midwest Research Inst., Kansas City, MO., and Department of Veterans Affairs Medical Center, Leavenworth, KS
- Country of Publication:
- United States
- Language:
- English
Similar Records
Dioxins and dibenzofurans in blood and adipose tissue of Agent Orange-exposed Vietnam veterans and matched controls
Serum 2,3,7,8-tetrachlorodibenzo-p-dioxin levels in US Army Vietnam-era veterans. The Centers for Disease Control Veterans Health Studies
Related Subjects
BENZOFURANS
METABOLISM
DIOXIN
ADIPOSE TISSUE
BIOLOGICAL MARKERS
COMPARATIVE EVALUATIONS
HEALTH HAZARDS
MILITARY PERSONNEL
TISSUE DISTRIBUTION
ANIMAL TISSUES
BODY
CONNECTIVE TISSUE
DISTRIBUTION
FURANS
HAZARDS
HETEROCYCLIC COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
PERSONNEL
TISSUES
560300* - Chemicals Metabolism & Toxicology