skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Pattern-evoked potentials and optic nerve fiber loss in monocular laser-induced glaucoma

Abstract

ERG and VEP responses to counterphase checkerboard stimuli were obtained from cynomolgus monkeys with monocular glaucoma induced by laser photocoagulation of the trabecular meshwork. The glaucomatous eyes showed reductions of PERG amplitude that were directly related to the histologically defined nerve damage. VEP amplitudes were also reduced in the glaucomatous eyes, but were more variable and less affected by damage than the PERG responses. An acute increase in eye pressure to 40 mm Hg in eyes without damage had no detectable effect on PERG amplitudes.

Authors:
; ; ; ;
Publication Date:
Research Org.:
Johns Hopkins Univ. School of Medicine, Baltimore, MD (USA)
OSTI Identifier:
5713545
Resource Type:
Journal Article
Journal Name:
Invest. Ophthalmol. Visual Sci.; (United States)
Additional Journal Information:
Journal Volume: 30:5
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; EYES; SENSITIVITY; LASER RADIATION; BIOLOGICAL EFFECTS; LASERS; MONKEYS; NERVES; SENSE ORGANS DISEASES; ANIMALS; BODY; BODY AREAS; DISEASES; ELECTROMAGNETIC RADIATION; FACE; HEAD; MAMMALS; NERVOUS SYSTEM; ORGANS; PRIMATES; RADIATIONS; SENSE ORGANS; VERTEBRATES; 560400* - Other Environmental Pollutant Effects

Citation Formats

Johnson, M A, Drum, B A, Quigley, H A, Sanchez, R M, and Dunkelberger, G R. Pattern-evoked potentials and optic nerve fiber loss in monocular laser-induced glaucoma. United States: N. p., 1989. Web.
Johnson, M A, Drum, B A, Quigley, H A, Sanchez, R M, & Dunkelberger, G R. Pattern-evoked potentials and optic nerve fiber loss in monocular laser-induced glaucoma. United States.
Johnson, M A, Drum, B A, Quigley, H A, Sanchez, R M, and Dunkelberger, G R. 1989. "Pattern-evoked potentials and optic nerve fiber loss in monocular laser-induced glaucoma". United States.
@article{osti_5713545,
title = {Pattern-evoked potentials and optic nerve fiber loss in monocular laser-induced glaucoma},
author = {Johnson, M A and Drum, B A and Quigley, H A and Sanchez, R M and Dunkelberger, G R},
abstractNote = {ERG and VEP responses to counterphase checkerboard stimuli were obtained from cynomolgus monkeys with monocular glaucoma induced by laser photocoagulation of the trabecular meshwork. The glaucomatous eyes showed reductions of PERG amplitude that were directly related to the histologically defined nerve damage. VEP amplitudes were also reduced in the glaucomatous eyes, but were more variable and less affected by damage than the PERG responses. An acute increase in eye pressure to 40 mm Hg in eyes without damage had no detectable effect on PERG amplitudes.},
doi = {},
url = {https://www.osti.gov/biblio/5713545}, journal = {Invest. Ophthalmol. Visual Sci.; (United States)},
number = ,
volume = 30:5,
place = {United States},
year = {Mon May 01 00:00:00 EDT 1989},
month = {Mon May 01 00:00:00 EDT 1989}
}