Evolution of thyroid /sup 127/I stores measured by X-ray fluorescence in subacute thyroiditis
Evaluation of the thyroid iodine content by x-ray fluorescence was performed in 13 patients throughout the course of subacute thyroiditis. In the initial hyperthyroid phase of the disease, the iodine stores of the thyroid were not completely depleted. The iodine content (6.5 +/- 3 mg) was about 2.5 times lower than normal values when thyroiditis had developed in a normal thyroid (10 patients); in 3 patients with goiter; it was elevated (29.6 +/- 6.7 mg) but was still within the normal range of euthyroid goitrous patients. After clinical remission, the iodine content of the gland increased only in two patients (+105% and +43% over the initial value, respectively). For the other patients, the iodine content decreased (from -5% to -100% of the initial value). Restoration of iodine stores occurred subsequently and appeared to be a slow and progressive phenomenon; in six patients the iodine content was still below normal values 12 months after clinical remission (6.6 +/- 1.6 mg). These data suggest that the course of subactue thyroiditis might be longer than would appear from the clinical data, the hormonal assays, or the radioactive thyroid uptake data.
- Research Organization:
- Inst. Gustave-Roussy, Villejuif Cedex, France
- OSTI ID:
- 5678897
- Journal Information:
- J. Clin. Endocrinol. Metab.; (United States), Vol. 54:1
- Country of Publication:
- United States
- Language:
- English
Similar Records
Typical and atypical (silent) subacute thyroiditis in a wife and husband
RADIOIODINE IN DIAGNOSIS AND THERAPY OF HYPERTHYROIDISM CAUSED BY HYPERFUNCTIONING THYROID ADENOMA
Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
IODINE
X-RAY FLUORESCENCE ANALYSIS
IODINE 127
UPTAKE
EXPERIMENTAL DATA
GOITER
PATIENTS
THYROID
THYROIDITIS
TRACER TECHNIQUES
BODY
CHEMICAL ANALYSIS
DATA
DISEASES
ELEMENTS
ENDOCRINE DISEASES
ENDOCRINE GLANDS
GLANDS
HALOGENS
INFORMATION
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
NONDESTRUCTIVE ANALYSIS
NONMETALS
NUCLEI
NUMERICAL DATA
ODD-EVEN NUCLEI
ORGANS
STABLE ISOTOPES
X-RAY EMISSION ANALYSIS
551001* - Physiological Systems- Tracer Techniques
550601 - Medicine- Unsealed Radionuclides in Diagnostics