Polychlorinated biphenyls, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (p,p{prime}-DDT) and 1,1-dichloro-2,2-bis(p-chlorophenyl)-ethylene (p,p{prime}-DDE) in human plasma related to fish consumption

Asplund, L; Eriksson, U; Jansson, B; Wideqvist, U; Svensson, B G; Nilsson, A; Skerfving, S; Jensen, S

doi:10.1080/00039896.1994.9955004

Title: Polychlorinated biphenyls, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (p,p{prime}-DDT) and 1,1-dichloro-2,2-bis(p-chlorophenyl)-ethylene (p,p{prime}-DDE) in human plasma related to fish consumption

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Abstract

Fatty fish species, e.g., salmon and herring, in the Baltic Sea have high levels of polychlorinated biphenyls (PCBs) and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (p,p{prime}-DDT), and its main metabolite: 1,1-dichloro-2,2-bis(p-chlorophenyl)-ethylene (p,p{prime}-DDE). We determined levels of 10 different PCB congeners, including non- and mono-ortho-PCBs, as well as DDT and DDE, in human blood plasma from 37 subjects with varying intake of fish (0-1 750 g/wk) from the Baltic Sea. With respect to all of the PCB congeners we investigated, as well as for DDT and DDE, there were statistically significant associations with fish intake. Thus, fish from the Baltic Sea is a major source of exposure to these compounds in Swedes. Polychlorinated dibenzo-p-dioxins (PCDD) and dibenzofurans (PCDF) had been determined earlier in 29 of the subjects. The PCB contribution to {open_quotes}dioxin-like{close_quotes} effects among high consumers of fish (calculated as Nordic TCDD equivalents) was almost 80%, whereas that from PCDD and PCDF was only 20%. 32 refs., 3 figs., 9 tabs.

Authors:

Asplund, L; Eriksson, U; Jansson, B; Wideqvist, U ^[1]; Svensson, B G; Nilsson, A; Skerfving, S ^[2]; Jensen, S ^[3]

Stockholm Univ., Solna (Sweden)
Univ. Hospital, Lund (Sweden)
Stockholm Univ. (Sweden)

Publication Date:: Tue Nov 01 00:00:00 EST 1994

Sponsoring Org.:: USDOE

OSTI Identifier:: 56743

Resource Type:: Journal Article

Journal Name:: Archives of Environmental Health

Additional Journal Information:: Journal Volume: 49; Journal Issue: 6; Other Information: PBD: Nov-Dec 1994

Country of Publication:: United States

Language:: English

Subject:: 56 BIOLOGY AND MEDICINE, APPLIED STUDIES; 55 BIOLOGY AND MEDICINE, BASIC STUDIES; BLOOD PLASMA; QUANTITATIVE CHEMICAL ANALYSIS; POLYCHLORINATED BIPHENYLS; ENVIRONMENTAL EXPOSURE PATHWAY; BIOLOGICAL ACCUMULATION; DDT; SALMON; FOOD CHAINS

Citation Formats


                    Asplund, L, Eriksson, U, Jansson, B, Wideqvist, U, Svensson, B G, Nilsson, A, Skerfving, S, and Jensen, S. Polychlorinated biphenyls, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (p,p{prime}-DDT) and 1,1-dichloro-2,2-bis(p-chlorophenyl)-ethylene (p,p{prime}-DDE) in human plasma related to fish consumption.  United States: N. p., 1994. 
        Web.  doi:10.1080/00039896.1994.9955004.

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                    Asplund, L, Eriksson, U, Jansson, B, Wideqvist, U, Svensson, B G, Nilsson, A, Skerfving, S, & Jensen, S. Polychlorinated biphenyls, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (p,p{prime}-DDT) and 1,1-dichloro-2,2-bis(p-chlorophenyl)-ethylene (p,p{prime}-DDE) in human plasma related to fish consumption.  United States.  https://doi.org/10.1080/00039896.1994.9955004

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                    Asplund, L, Eriksson, U, Jansson, B, Wideqvist, U, Svensson, B G, Nilsson, A, Skerfving, S, and Jensen, S. 1994.  
        "Polychlorinated biphenyls, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (p,p{prime}-DDT) and 1,1-dichloro-2,2-bis(p-chlorophenyl)-ethylene (p,p{prime}-DDE) in human plasma related to fish consumption".  United States.  https://doi.org/10.1080/00039896.1994.9955004.

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@article{osti_56743,

  title        = {Polychlorinated biphenyls, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (p,p{prime}-DDT) and 1,1-dichloro-2,2-bis(p-chlorophenyl)-ethylene (p,p{prime}-DDE) in human plasma related to fish consumption},

  author       = {Asplund, L and Eriksson, U and Jansson, B and Wideqvist, U and Svensson, B G and Nilsson, A and Skerfving, S and Jensen, S},

  abstractNote = {Fatty fish species, e.g., salmon and herring, in the Baltic Sea have high levels of polychlorinated biphenyls (PCBs) and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (p,p{prime}-DDT), and its main metabolite: 1,1-dichloro-2,2-bis(p-chlorophenyl)-ethylene (p,p{prime}-DDE). We determined levels of 10 different PCB congeners, including non- and mono-ortho-PCBs, as well as DDT and DDE, in human blood plasma from 37 subjects with varying intake of fish (0-1 750 g/wk) from the Baltic Sea. With respect to all of the PCB congeners we investigated, as well as for DDT and DDE, there were statistically significant associations with fish intake. Thus, fish from the Baltic Sea is a major source of exposure to these compounds in Swedes. Polychlorinated dibenzo-p-dioxins (PCDD) and dibenzofurans (PCDF) had been determined earlier in 29 of the subjects. The PCB contribution to {open_quotes}dioxin-like{close_quotes} effects among high consumers of fish (calculated as Nordic TCDD equivalents) was almost 80%, whereas that from PCDD and PCDF was only 20%. 32 refs., 3 figs., 9 tabs.},

  doi          = {10.1080/00039896.1994.9955004},

  url          = {https://www.osti.gov/biblio/56743},
  journal      = {Archives of Environmental Health},
number       = 6,

  volume       = 49,

  place        = {United States},

  year         = {Tue Nov 01 00:00:00 EST 1994},

  month        = {Tue Nov 01 00:00:00 EST 1994}

}

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