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Title: Effect of exhaustive exercise on myocardial performance

Abstract

Possible changes in cardiac functional capacity in the intact heart following prolonged exhaustive exercise are investigated. Cardiac output, coronary blood flow, aortic blood pressure, left ventricular pressure, maximum rate of left ventricular pressure development and maximum rate of left ventricular pressure relaxation were measured in eight chronically instrumented adult mongrel dogs run at a constant work load to exhaustion signalled by the animals' refusal or inability to continue. All cardiovascular parameters, with the exception of stroke volume, are found to increase significantly during the transition from rest to steady-state exercise at about 75% of maximum heart rate. In the transition from steady state to exhaustion, only the maximum rates of left ventricular pressure development and relaxation are observed to increase significantly, while all other values exhibited no significant change. Similarly, no significant changes are observed in measurements of maximum cardiac parameters before and after exhaustion. Results indicate that cardiac function and hemodynamic parameters are not depressed at exhaustion in dogs despite observed ultrastructural changes.

Authors:
; ;
Publication Date:
Research Org.:
California University, Los Angeles
OSTI Identifier:
5672986
Resource Type:
Journal Article
Journal Name:
J. Appl. Physiol.: Respir., Environ. Exercise Physiol.; (United States)
Additional Journal Information:
Journal Volume: 51
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; CARDIOVASCULAR SYSTEM; BIOLOGICAL FATIGUE; DOGS; BLOOD; BLOOD PRESSURE; EXERCISE; MYOCARDIUM; VOLUME; ANIMALS; BIOLOGICAL MATERIALS; BODY; BODY FLUIDS; HEART; MAMMALS; MATERIALS; MUSCLES; ORGANS; VERTEBRATES; 551000* - Physiological Systems

Citation Formats

Grimditch, G K, Barnard, R J, and Duncan, H W. Effect of exhaustive exercise on myocardial performance. United States: N. p., 1981. Web.
Grimditch, G K, Barnard, R J, & Duncan, H W. Effect of exhaustive exercise on myocardial performance. United States.
Grimditch, G K, Barnard, R J, and Duncan, H W. 1981. "Effect of exhaustive exercise on myocardial performance". United States.
@article{osti_5672986,
title = {Effect of exhaustive exercise on myocardial performance},
author = {Grimditch, G K and Barnard, R J and Duncan, H W},
abstractNote = {Possible changes in cardiac functional capacity in the intact heart following prolonged exhaustive exercise are investigated. Cardiac output, coronary blood flow, aortic blood pressure, left ventricular pressure, maximum rate of left ventricular pressure development and maximum rate of left ventricular pressure relaxation were measured in eight chronically instrumented adult mongrel dogs run at a constant work load to exhaustion signalled by the animals' refusal or inability to continue. All cardiovascular parameters, with the exception of stroke volume, are found to increase significantly during the transition from rest to steady-state exercise at about 75% of maximum heart rate. In the transition from steady state to exhaustion, only the maximum rates of left ventricular pressure development and relaxation are observed to increase significantly, while all other values exhibited no significant change. Similarly, no significant changes are observed in measurements of maximum cardiac parameters before and after exhaustion. Results indicate that cardiac function and hemodynamic parameters are not depressed at exhaustion in dogs despite observed ultrastructural changes.},
doi = {},
url = {https://www.osti.gov/biblio/5672986}, journal = {J. Appl. Physiol.: Respir., Environ. Exercise Physiol.; (United States)},
number = ,
volume = 51,
place = {United States},
year = {Sun Nov 01 00:00:00 EST 1981},
month = {Sun Nov 01 00:00:00 EST 1981}
}