PET as a tool in the clinical evaluation of pituitary adenomas

Journal Article · Mon Apr 01 00:00:00 EST 1991 · Journal of Nuclear Medicine; (United States)

OSTI ID:5670729

Bergstroem, M M; Muhr, C; Lundberg, P O; B4, Langstroem ^[1]

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1. Uppsala Univ. PET Center (Sweden)

Positron emission tomography (PET) was used in over 400 examinations in patients with pituitary adenoma. It was demonstrated that PET with carbon-11-methionine can give valuable complementary information in the diagnosis of this tumor due to PET's ability to adequately depict viable tumor tissue in contrast to fibrosis, cysts and necrosis. Furthermore, PET with dopamine D2 receptor ligands can characterize the degree of receptor binding and thus give information as to the prerequisites for dopamine agonist treatment. Most important is the very high sensitivity given by PET with carbon-11-methionine in the evaluation of treatment effects. It is concluded that when properly used PET can be fully justified in the clinical handling of patients with pituitary adenomas and other intracranial tumors.

• OSTI ID: 5670729
• Journal Information: Journal of Nuclear Medicine; (United States), Vol. 32:4; ISSN 0161-5505
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ADENOMAS
DIAGNOSIS
PITUITARY GLAND
POSITRON COMPUTED TOMOGRAPHY
DIAGNOSTIC USES
CARBON ISOTOPES
METHIONINE
PATIENTS
AMINO ACIDS
BODY
CARBOXYLIC ACIDS
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
EMISSION COMPUTED TOMOGRAPHY
ENDOCRINE GLANDS
GLANDS
ISOTOPES
LIPOTROPIC FACTORS
NEOPLASMS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
ORGANS
TOMOGRAPHY
USES
550601* - Medicine- Unsealed Radionuclides in Diagnostics