Two DNA repair and recombination genes in Saccharomyces cerevisiae, RAD52 and RAD54, are induced during meiosis
Abstract
The DNA repair and recombination genes of Saccharomyces cerevisiae, RAD52 and RAD54, were transcriptionally induced approximately 10- to 15-fold in sporulating MATa/{alpha} cells. Congenic MATa/a cells, which did not sporulate, did not show similar increases. Assays of {beta}-galactosidase activity in strains harboring either a RAD52- or RAD54-lacZ gene fusion indicated that this induction occurred at a time concomitant with a commitment to meiotic recombination, as measured by prototroph formation from his1 heteroalleles.
- Authors:
-
- Univ. of California, Berkeley (United States)
- Lawrence Berkeley Lab., CA (United States)
- Publication Date:
- OSTI Identifier:
- 5623786
- DOE Contract Number:
- AC03-76SF00098
- Resource Type:
- Journal Article
- Journal Name:
- Molecular and Cellular Biology; (United States)
- Additional Journal Information:
- Journal Volume: 9:7; Journal ID: ISSN 0270-7306
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; DNA REPAIR; MOLECULAR BIOLOGY; GENE RECOMBINATION; BACTERIAL SPORES; BIOLOGICAL FUNCTIONS; GENES; MEIOSIS; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION; BIOLOGICAL RECOVERY; BIOLOGICAL REPAIR; CELL DIVISION; EUMYCOTA; FUNGI; MICROORGANISMS; PLANTS; RECOVERY; REPAIR; SACCHAROMYCES; SPORES; YEASTS; 550200* - Biochemistry; 551000 - Physiological Systems
Citation Formats
Cole, G M, Mortimer, R K, and Schild, D. Two DNA repair and recombination genes in Saccharomyces cerevisiae, RAD52 and RAD54, are induced during meiosis. United States: N. p., 1989.
Web. doi:10.1128/MCB.9.7.3101.
Cole, G M, Mortimer, R K, & Schild, D. Two DNA repair and recombination genes in Saccharomyces cerevisiae, RAD52 and RAD54, are induced during meiosis. United States. https://doi.org/10.1128/MCB.9.7.3101
Cole, G M, Mortimer, R K, and Schild, D. 1989.
"Two DNA repair and recombination genes in Saccharomyces cerevisiae, RAD52 and RAD54, are induced during meiosis". United States. https://doi.org/10.1128/MCB.9.7.3101.
@article{osti_5623786,
title = {Two DNA repair and recombination genes in Saccharomyces cerevisiae, RAD52 and RAD54, are induced during meiosis},
author = {Cole, G M and Mortimer, R K and Schild, D},
abstractNote = {The DNA repair and recombination genes of Saccharomyces cerevisiae, RAD52 and RAD54, were transcriptionally induced approximately 10- to 15-fold in sporulating MATa/{alpha} cells. Congenic MATa/a cells, which did not sporulate, did not show similar increases. Assays of {beta}-galactosidase activity in strains harboring either a RAD52- or RAD54-lacZ gene fusion indicated that this induction occurred at a time concomitant with a commitment to meiotic recombination, as measured by prototroph formation from his1 heteroalleles.},
doi = {10.1128/MCB.9.7.3101},
url = {https://www.osti.gov/biblio/5623786},
journal = {Molecular and Cellular Biology; (United States)},
issn = {0270-7306},
number = ,
volume = 9:7,
place = {United States},
year = {Sat Jul 01 00:00:00 EDT 1989},
month = {Sat Jul 01 00:00:00 EDT 1989}
}
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