Cerebral blood flow and brain atrophy correlated by xenon contrast CT scanning
Correlations between cerebral blood flow (CBF) measured during stable xenon contrast CT scanning and standard CT indices of brain atrophy were investigated in the patients with senile dementia of Alzheimer type, multi-infarct dementia and idiopathic Parkinson's disease. Compared to age-matched normal volunteers, significant correlations were found in patients with idiopathic Parkinson's disease between cortical and subcortical gray matter blood flow and brain atrophy estimated by the ventricular body ratio, and mild to moderate brain atrophy were correlated with stepwise CBF reductions. However, in patients with senile dementia of Alzheimer type and multi-infarct dementia, brain atrophy was not associated with stepwise CBF reductions. Overall correlations between brain atrophy and reduced CBF were weak. Mild degrees of brain atrophy are not always associated with reduced CBF.
- Research Organization:
- Veterans Administration Medical Center, Houston, TX
- OSTI ID:
- 5618876
- Journal Information:
- Comput. Radiol.; (United States), Vol. 6
- Country of Publication:
- United States
- Language:
- English
Similar Records
High-resolution nuclear magnetic resonance imaging and single photon emission computerized tomography--cerebral blood flow in a case of pure sensory stroke and mild dementia owing to subcortical arteriosclerotic encephalopathy (Binswanger's disease)
Senile dementia of the Binswanger type: a vascular form of dementia in the elderly
Related Subjects
BRAIN
ATROPHY
CAT SCANNING
BLOOD FLOW
CORRELATIONS
NERVOUS SYSTEM DISEASES
PATIENTS
XENON
BODY
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DISEASES
ELEMENTS
FLUIDS
GASES
NERVOUS SYSTEM
NONMETALS
ORGANS
PATHOLOGICAL CHANGES
RARE GASES
TOMOGRAPHY
550601* - Medicine- Unsealed Radionuclides in Diagnostics