Distribution of polonium-210 in the human lung. [Comparison between smokers and non-smokers]
Polonium-210 has been measured in the tracheobronchial tree and parenchyma of cigarette smokers and nonsmokers in order to determine whether this ..cap alpha.. emitter is retained in smokers. The ratio of /sup 210/Po concentration in the tracheobronchial tree (T) to that in the lung parenchyma (P) in nonsmokers is T/P = 2.7 +- 0.5. The ratio in smokers is T/P = 1.1 +- 0.2. The difference in these ratios can be related to retention of /sup 210/Po, or its /sup 210/Pb precursor in the parenchymal tissue. About 5 pCi deposited and retained on alveolar surfaces and an average excess of 0.3 pCi /sup 210/Po retained on the tracheobronchial tree is estimated for smokers. Measurements in exsmokers result in a ratio (T/P) = 0.8 +- 0.4 and is possibly related to long-term retention of deposited /sup 210/Pb in alveolar tissue.
- Research Organization:
- New York Univ. Medical Center, NY
- OSTI ID:
- 5615708
- Journal Information:
- Radiat. Res.; (United States), Vol. 19:1
- Country of Publication:
- United States
- Language:
- English
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37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
BRONCHI
RADIOCHEMICAL ANALYSIS
RADIONUCLIDE KINETICS
LEAD 210
TISSUE DISTRIBUTION
LUNGS
POLONIUM 210
TRACHEA
COMPARATIVE EVALUATIONS
DEPOSITION
EXPERIMENTAL DATA
INHALATION
MAN
QUANTITY RATIO
TABLES
TOBACCO SMOKES
AEROSOLS
ALPHA DECAY RADIOISOTOPES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CHEMICAL ANALYSIS
COLLOIDS
DATA
DATA FORMS
DAYS LIVING RADIOISOTOPES
DISPERSIONS
DISTRIBUTION
EVEN-EVEN NUCLEI
HEAVY NUCLEI
INFORMATION
INTAKE
ISOTOPES
LEAD ISOTOPES
MAMMALS
NUCLEI
NUMERICAL DATA
ORGANS
POLONIUM ISOTOPES
PRIMATES
RADIOISOTOPES
RESIDUES
RESPIRATORY SYSTEM
SMOKES
SOLS
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560171* - Radiation Effects- Nuclide Kinetics & Toxicology- Man- (-1987)
400103 - Radiometric & Radiochemical Procedures- (-1987)