A simple and rapid method for evaluating the survival of xeroderma pigmentosum lymphoid lines after irradiation with ultraviolet light
Journal Article
·
· In Vitro; (United States)
A simple, rapid, and reproducible test has been developed to measure the viability of cells after irradiation with ultraviolet light (UV). Epstein-Barr virus-transformed lymphoid lines, derived from patients with xeroderma pigmentosum (XP), were irradiated with UV, and the post-UV viability of the lymphoid lines was determined by the trypan blue dye exclusion method. The relative post-UV survival of the patients' lymphoid lines was similar to the relative post-UV survival of the patients' fibroblast strains.
- OSTI ID:
- 5612563
- Journal Information:
- In Vitro; (United States), Vol. 17:4
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
VIABILITY
MEASURING METHODS
XP CELLS
BIOLOGICAL RADIATION EFFECTS
CELL CULTURES
CELL KILLING
DOSE-RESPONSE RELATIONSHIPS
FIBROBLASTS
LYMPHATIC SYSTEM
SURVIVAL TIME
ULTRAVIOLET RADIATION
ANIMAL CELLS
BIOLOGICAL EFFECTS
CONNECTIVE TISSUE CELLS
ELECTROMAGNETIC RADIATION
RADIATION EFFECTS
RADIATIONS
SOMATIC CELLS
560121* - Radiation Effects on Cells- External Source- (-1987)
550300 - Cytology
59 BASIC BIOLOGICAL SCIENCES
VIABILITY
MEASURING METHODS
XP CELLS
BIOLOGICAL RADIATION EFFECTS
CELL CULTURES
CELL KILLING
DOSE-RESPONSE RELATIONSHIPS
FIBROBLASTS
LYMPHATIC SYSTEM
SURVIVAL TIME
ULTRAVIOLET RADIATION
ANIMAL CELLS
BIOLOGICAL EFFECTS
CONNECTIVE TISSUE CELLS
ELECTROMAGNETIC RADIATION
RADIATION EFFECTS
RADIATIONS
SOMATIC CELLS
560121* - Radiation Effects on Cells- External Source- (-1987)
550300 - Cytology