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Title: Prospects for DNA methods to measure human heritable mutation rates

A workshop cosponsored by ICPEMC and the US Department of Energy was held in Alta, Utah, December 9-13, 1984 to examine the extent to which DNA-oriented methods might provide new approaches to the important but intractable problem of measuring mutation rates in control and exposed human populations. The workshop identified and analyzed six DNA methods for detection of human heritable mutation, including several created at the meeting, and concluded that none of the methods combine sufficient feasibility and efficiency to be recommended for general application. 8 refs.
Authors:
Publication Date:
OSTI Identifier:
5608610
Report Number(s):
UCRL-92242; CONF-8506137-5
ON: DE85014555
DOE Contract Number:
W-7405-ENG-48
Resource Type:
Conference
Resource Relation:
Conference: 4. international conference on environmental mutagens, Stockholm, Sweden, 24 Jun 1985
Research Org:
Lawrence Livermore National Lab., CA (USA)
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; MAN; MUTATION FREQUENCY; TESTING; DNA SEQUENCING; ELECTROPHORESIS; ENDONUCLEASES; ANIMALS; DNA-ASE; ENZYMES; ESTERASES; HYDROLASES; MAMMALS; PHOSPHODIESTERASES; PRIMATES; STRUCTURAL CHEMICAL ANALYSIS; VERTEBRATES 560151* -- Radiation Effects on Animals-- Man; 550401 -- Genetics-- Tracer Techniques