Chromosomal aberrations in onion (Allium cepa) induced by water chlorination by-products
It has recently come to light that water chlorination generates mutagens and carcinogens. The mutagenicity of nonvolatile mutagenic by-products of water chlorination has been demonstrated in short-term biological testings. The predictive value of short-term tests is considerably enhanced by the use of more than one test system. A scientifically stringent approach in formulating a testing program for the assessment of genotoxins is to rely on tests that directly measure gene mutations and chromosome alterations. Chromosome aberrations (CA) become such a relevant bioassay. The CA measurement in the allium test is suitable for measuring the cytogenotoxic potential of chemicals present in water; it is simple, cheap, sensitive, and it does not require a generally undefined step of concentrating chemicals present in polluted waters. In the present investigation CA in Allium were chosen for the detection of mutagenic potential of a polluted river waters before and after the under-breakpoint chlorination.
- Research Organization:
- Rudjer Boskovic Institute, Zagreb, Yugoslavia
- OSTI ID:
- 5604257
- Journal Information:
- Bull. Environ. Contam. Toxicol.; (United States), Vol. 34:1
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
ALLIUM CEPA
CHROMOSOMAL ABERRATIONS
CHLORINATION
BIOLOGICAL EFFECTS
WATER POLLUTION
MUTAGEN SCREENING
FRESH WATER
ONIONS
RIVERS
SODIUM CHLORIDES
ALKALI METAL COMPOUNDS
CHEMICAL REACTIONS
CHLORIDES
CHLORINE COMPOUNDS
FOOD
HALIDES
HALOGEN COMPOUNDS
HALOGENATION
HYDROGEN COMPOUNDS
MUTATIONS
OXYGEN COMPOUNDS
PLANTS
POLLUTION
SCREENING
SODIUM COMPOUNDS
STREAMS
SURFACE WATERS
VEGETABLES
WATER
560303* - Chemicals Metabolism & Toxicology- Plants- (-1987)