Studies of delayed hypersensitivity responses in children in an industrialized region of Italy

Journal Article · Sat Jun 01 00:00:00 EDT 1991 · Annals of Allergy; (United States)

OSTI ID:5590589

La Rosa, M; Mancuso, G R; Greco, D; Di Paola, M; Schiliro, G; Bagnato, G F; Bellanti, J A ^[1]

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1. Department of Pediatrics, University of Catania (Italy)

The purpose of the present study was to evaluate the effects of chronic exposure to chemical pollutants on cell mediated immune responses in a pediatric population living in Priolo, an industrialized area of Italy, by means of skin test (Multitest CMI). The results suggest that children living in Priolo display significantly lower delayed type hypersensitivity (DTH) response than those seen in an age-matched and socioeconomically similar group of children living in Taormina, a nonindustrialized area. The lowered incidence of DTH scores in Priolo is not due to the number of positive skin test responses to individual antigens, but rather to the size of individual reactions.

• OSTI ID: 5590589
• Journal Information: Annals of Allergy; (United States), Vol. 66:6; ISSN 0003-4738
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
RETICULOENDOTHELIAL SYSTEM
SENSITIVITY
XENOBIOTICS
HEALTH HAZARDS
CHILDREN
ENVIRONMENTAL EXPOSURE
IMMUNE REACTIONS
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ITALY
AGE GROUPS
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EUROPE
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560300* - Chemicals Metabolism & Toxicology