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Title: A conveniently prepared Tc-99m resin for semisolid gastric emptying studies

Journal Article · · J. Nucl. Med.; (United States)
OSTI ID:5550922

A polystyrene resin, suitable for semi-solid gastric emptying studies, was rapidly (less than 20 min) and conveniently prepared using commercially available reagents. Using the outlined procedure, Chelex-100 resin bound Tc-99m with greater than 98% labeling efficiency. The resulting Tc-99m Chelex-100 resin demonstrated excellent in vitro and in vivo stability. The clinical application of Tc-99m Chelex-100 resin, mixed with oatmeal, was tested in normal subjects and in various patient groups, including diabetic autonomic neuropathy, pyloric obstruction, postoperative dumping syndrome, and morbidly obese patients before and after gastroplasty.

Research Organization:
University of Michigan, Ann Arbor
OSTI ID:
5550922
Journal Information:
J. Nucl. Med.; (United States), Vol. 24:6
Country of Publication:
United States
Language:
English