Neutron diffraction of. cap alpha. ,. beta. and. gamma. cyclodextrins: hydrogen bonding patterns

Conference · Sat Jan 01 00:00:00 EST 1983

OSTI ID:5528251

Hingerty, B E; Klar, B; Hardgrove, G; Betzel, C; Saenger, W

Cyclodextrins (CD's) are torus-shaped molecules composed of six (..cap alpha..), seven (..beta..) or eight (..gamma..) (1 ..-->.. 4) linked glucoses. ..cap alpha..-CD has been shown to have two different structures with well-defined hydrogen bonds, one tense and the other relaxed. An induced-fit-like mechanism for ..cap alpha..-CD complex formation has been proposed. Circular hydrogen bond networks have also been found for ..cap alpha..-CD due to the energetically favored cooperative effect. ..beta..-CD with a disordered water structure possesses an unusual flip-flop hydrogen bonding system of the type O-H H-O representing an equilibrium between two states; O-H O reversible H-O. ..gamma..-CD with a disordered water structure similar to ..beta..-CD also possesses the flip-flop hydrogen bond. This study demonstrates that hydrogen bonds are operative in disordered systems and display dynamics even in the solid state.

• Research Organization: Oak Ridge National Lab., TN (USA); Institut Max von Laue - Paul Langevin, 38 - Grenoble (France); Saint Olaf Coll., Northfield, MN (USA); Freie Univ. Berlin (Germany, F.R.). Inst. fuer Kristallographie
• DOE Contract Number: W-7405-ENG-26
• OSTI ID: 5528251
• Report Number(s): CONF-8306144-1; ON: DE84003175
• Resource Relation: Conference: Symposium on conversation in biomolecular stereodynamics III, Albany, NY, USA, 7 Jun 1983
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
OLIGOSACCHARIDES
CHEMICAL REACTION KINETICS
MOLECULAR STRUCTURE
NEUTRON DIFFRACTION
X-RAY DIFFRACTION
CHELATES
CRYSTAL STRUCTURE
DEUTERIUM COMPOUNDS
GLUCOSE
HYDROLYSIS
LABELLING
VAN DER WAALS FORCES
ALDEHYDES
CARBOHYDRATES
CHEMICAL REACTIONS
COHERENT SCATTERING
COMPLEXES
DECOMPOSITION
DIFFRACTION
HEXOSES
HYDROGEN COMPOUNDS
KINETICS
LYSIS
MONOSACCHARIDES
ORGANIC COMPOUNDS
REACTION KINETICS
SACCHARIDES
SCATTERING
SOLVOLYSIS
550201* - Biochemistry- Tracer Techniques