Screening for breast cancer in a high-risk series
- University of Rochester School of Medicine and Dentistry, NY
A unique cohort of women at increased risk of breast cancer because of prior X-ray treatment of acute mastitis and their selected high-risk siblings were offered periodic breast cancer screening including physical examination of the breasts, mammography, and thermography. Twelve breast cancers were detected when fewer than four would have been expected based on age-specific breast cancer detection rates from the National Cancer institute/American Cancer Society Breast Cancer Demonstration Detection Projects. Mammograpy was positive in all cases but physical examination was positive in only three cases. Thermography was an unreliable indicator of disease. Given the concern over radiation-induced risk, use of low-dose technique and of criteria for participation that select women at high risk of breast cancer will maximize the benefit/risk ratio for mammography screening.
- OSTI ID:
- 5503975
- Journal Information:
- J. Surg. Oncol.; (United States), Vol. 19:1
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
MAMMARY GLANDS
CARCINOGEN SCREENING
RADIOTHERAPY
HAZARDS
X RADIATION
DELAYED RADIATION EFFECTS
DIAGNOSIS
MEDICAL SURVEILLANCE
NEOPLASMS
PATIENTS
WOMEN
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
DISEASES
ELECTROMAGNETIC RADIATION
FEMALES
GLANDS
IONIZING RADIATIONS
MAMMALS
MAN
MEDICINE
NUCLEAR MEDICINE
ORGANS
PRIMATES
RADIATION EFFECTS
RADIATIONS
RADIOLOGY
SCREENING
SURVEILLANCE
THERAPY
VERTEBRATES
550603* - Medicine- External Radiation in Therapy- (1980-)